ArticleACS omega2022
Adsorption Behavior of a Gd-Based Metal-Organic Framework toward the Quercetin Drug: Effect of the Activation Condition.
Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed, 25 citations in OpenAlex.
- Enhanced separation of europium radionuclides from active solutions using a novel sorbent of gadolinium metal-organic framework.RSC advances · 2025Article
- Dual-Functioning Metal-Organic Frameworks: Methotrexate-Loaded Gadolinium MOFs as Drug Carriers and Radiosensitizers.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- 3D-Printed MOF Monoliths: Fabrication Strategies and Environmental Applications.Nano-micro letters · 2024Review
- Possible Sources of Trace Metals in Obese Females Living in Informal Settlements near Industrial Sites around Gauteng, South Africa.International journal of environmental research and public health · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A carboxylate gadolinium-based metal-organic framework (Gd-MOF) is an exceptional candidate for magnetic resonance imaging agents, but its low drug adsorption capacity hinders this MOF from being used as a theragnostic agent. In this work, the Gd-MOF was synthesized by a simple solvothermal method. Then, different activation situations, including various solvents over different time periods, were applied to enhance the specific surface area of the synthesized MOF. Different characterization analyses such as X-ray diffraction and Brunauer-Emmett-Teller along with experimental quercetin adsorption tests were done to study the crystalline and physical properties of various activated MOFs. In the following, the MOF activated by ethanol for 3 days (3d-E) was chosen as the best activated MOF due to its crystallinity, highest specific surface area, and drug adsorption capacity. More explorations were done for the selected MOF, including the drug adsorption isotherm, thermodynamics, and pH effect of adsorption. The results show that the activation process substantially affects the crystallinity, morphology, specific surface area, and drug adsorption capacity of Gd-MOFs. An optimized activation condition is proposed in this work, which shows an impressive enhancement of the specific surface area of Gd-MOFs just by simple solvent exchange method employment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.