Evidence map›Paper›PMID 36406503›Full record

ArticleACS omega2022

Chemodivergent Synthesis of Aza-Heterocycles with a Quarternary Carbon Center via [4 + 1] Annulation between Azoalkenes and α-Bromo Carbonyl Compounds.

Xiaoke Zhang, Haibo Wang, Ziwei Li, Yan Shu, Song Gan, Xuefang Zhang, Huawu Shao, Chaoyong Wang

Abstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoke ZhangCentral Laboratory, Chongqing University FuLing Hospital, Chongqing 408000, P.R. China.ORCID https://orcid.org/0000-0003-0423-5790
Haibo WangZhejiang Hongyuan Pharmaceutical Co., Ltd., Chem & APIs, Industrial Zone, Linhai, Taizhou 310001, Zhejiang, P.R. China.
Ziwei LiCentral Laboratory, Chongqing University FuLing Hospital, Chongqing 408000, P.R. China.
Yan ShuCentral Laboratory, Chongqing University FuLing Hospital, Chongqing 408000, P.R. China.
Song GanZunyi Medical University, Zunyi, Guizhou 563000, P.R. China.
Xuefang ZhangZunyi Medical University, Zunyi, Guizhou 563000, P.R. China.
Huawu ShaoNatural Products Research Centre, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 100045, P.R. China.
Chaoyong WangCentral Laboratory, Chongqing University FuLing Hospital, Chongqing 408000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An efficient [4 + 1] annulation reaction between in situ generated azoalkene intermediates and α-bromocarbonyls has been established. A series of skeletally diverse aza-heterocycles with a functionalized quaternary center were obtained in up to 89% yield under mild conditions.

Identifiers

PMID36406503
PMCPMC9670695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.