Evidence map›Paper›PMID 36406388›Full record

ArticleFrontiers in microbiology2022

Immunogenicity of the recombinant adenovirus fusion-expressing E0-E2 gene of the classical swine fever virus.

Heng Zhang, Dehua Yin, Huairui Qin, Ke Zhang, Zhaoyang Li, Guangchao Cui, Guangbin Ma, Peng Sun, Zhi Cao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Heng ZhangSwine Disease R&D Center, Shandong SINDER Technology Co., Ltd., Qingdao, China.
Dehua YinCollege of Animal Medicine, Qingdao Agricultural University, Qingdao, China.
Huairui QinCollege of Animal Medicine, Qingdao Agricultural University, Qingdao, China.
Ke ZhangCollege of Animal Medicine, Qingdao Agricultural University, Qingdao, China.
Zhaoyang LiSwine Disease R&D Center, Shandong SINDER Technology Co., Ltd., Qingdao, China.
Guangchao CuiSwine Disease R&D Center, Shandong SINDER Technology Co., Ltd., Qingdao, China.
Guangbin MaSwine Disease R&D Center, Shandong SINDER Technology Co., Ltd., Qingdao, China.
Peng SunYEBIO Bioengineering Co., Ltd of Qingdao, Qingdao, China.
Zhi CaoCollege of Animal Medicine, Qingdao Agricultural University, Qingdao, China.
Qingdao Agricultural University · CNShandong Sinder Technology Co., Ltd.Yebio Bioengineering (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenovirus vector vaccines have been the mainstream research direction of CSF vaccines, due to the replication deficiency of adenovirus vectors, achieving double effects with the safety of inactivated vaccines and the efficacy of live vaccines. Therefore, the E0 and E2 genes were expressed by an adenovirus vector, a recombinant adenovirus E0-E2 (rAd-E0-E2) vaccine was constructed, and the minimum immunization dose and immune duration period were determined in this study. Forty healthy piglets were randomly divided into 8 groups (

Indexed as

classical swine fever virusE0-E2 geneimmune durationminimum immunization doserecombinant adenovirus vaccine

Identifiers

PMID36406388
PMCPMC9673476
OpenAlexW4307511545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.