Evidence map›Paper›PMID 36406265›Full record

ArticleFrontiers in molecular biosciences2022

Leon Lufkin, Ankita Samanta, DeVaun Baker, Sina Lufkin, JesslynHope Schulze, Benjamin Ellis, Jillian Rose, Thomas Lufkin, Petra Kraus

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Leon LufkinDepartment of Statistics and Data Science, Yale University, New Haven, CT, United States.
Ankita SamantaDepartment of Biology, Clarkson University, Potsdam, NY, United States.
DeVaun BakerDepartment of Biology, Clarkson University, Potsdam, NY, United States.
Sina LufkinDepartment of Biology, Clarkson University, Potsdam, NY, United States.
JesslynHope SchulzeDepartment of Biology, Clarkson University, Potsdam, NY, United States.
Benjamin EllisDepartment of Biology, Clarkson University, Potsdam, NY, United States.
Jillian RoseDepartment of Biology, Clarkson University, Potsdam, NY, United States.
Thomas LufkinDepartment of Biology, Clarkson University, Potsdam, NY, United States.
Petra KrausDepartment of Biology, Clarkson University, Potsdam, NY, United States.
Clarkson University · USClark Art Institute · US

Funding

Genome-Wide Analysis of the Transcriptional Cooperation Between Runx2 And Runx3 During Skeletal DevelopmentR15HD099588 · NICHD · CLARKSON UNIVERSITY · PI LUFKIN, THOMAS · 2019 to 2019
$459k
NICHD NIH HHS R15 HD099588
6 · The paper itself

Abstract

Regenerative medicine aims to repair degenerate tissue through cell refurbishment with minimally invasive procedures. Adipose tissue (FAT)-derived stem or stromal cells are a convenient autologous choice for many regenerative cell therapy approaches. The intervertebral disc (IVD) is a suitable target. Comprised of an inner nucleus pulposus (NP) and an outer annulus fibrosus (AF), the degeneration of the IVD through trauma or aging presents a substantial socio-economic burden worldwide. The avascular nature of the mature NP forces cells to reside in a unique environment with increased lactate levels, conditions that pose a challenge to cell-based therapies. We assessed adipose and IVD tissue-derived stromal cells through

Indexed as

3D cultureadiposeannulus fibrosusintervertebral discnucleus pulposusregenerative medicinestromal celltranscriptome analysis

Identifiers

PMID36406265
PMCPMC9671658
OpenAlexW4309663243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.