ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2022
Assessment of risk factors associated with outpatient parenteral antimicrobial therapy (OPAT) complications: A retrospective cohort study.
Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Practice guidelines for outpatient parenteral antimicrobial therapy (OPAT) in Germany.Infection · 2025Guideline
- Safety and Efficacy of Outpatient Parenteral Antibiotic Therapy (OPAT) in Patients With Infective Endocarditis: A Systematic Review and Meta-Analysis.Clinical cardiology · 2025Pooled it
- A US Hospital-Perspective Decision-Analytic Model of Once-Weekly Rezafungin Versus Daily Echinocandin Therapy in Hospitalized Adults With Candidemia or Invasive Candidiasis: Potential Cost Savings From Earlier Discharge.Open forum infectious diseases · 2026Trial
- One if By Hand, Two if Orally: PICCing the Best Treatment Option.Open forum infectious diseases · 2024Trial
- Outpatient Parenteral Antimicrobial Therapy Practice Variability Across Veterans Affairs Hospitals.JAMA network open · 2026Article
- 2026 Updated good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults and children in the UK.JAC-antimicrobial resistance · 2026Review
- [Outpatient parenteral antimicrobial therapy: challenges and opportunities].Innere Medizin (Heidelberg, Germany) · 2026Article
- Propensity Score-Weighted Analysis of the Impact of Outpatient Parenteral Antimicrobial Therapy Plan Reconciliation on Unscheduled Care.Open forum infectious diseases · 2025Article
- Inpatient Cost Avoidance and Uncompensated Labor Associated With Different Outpatient Parenteral Antimicrobial Therapy Care Models.Open forum infectious diseases · 2025Article
- Outpatient Parenteral Antimicrobial Therapy Outcomes Metrics Assessment Survey.Open forum infectious diseases · 2025Article
- Review
- Outcome of outpatient parenteral antibiotic therapy (OPAT) program at a tertiary care hospital in India.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Current practices and challenges of outpatient parenteral antimicrobial therapy: a narrative review.The Journal of antimicrobial chemotherapy · 2024Review
- Shared Decision-Making for Partial Oral Antibiotic Treatment of Infective Endocarditis: A Case Series.Open forum infectious diseases · 2024Article
- Factors associated with loss to follow-up in outpatient parenteral antimicrobial therapy: A retrospective cohort study.Infection control and hospital epidemiology · 2024Article
- Making the EHR Work for You-Modifications of an Electronic Health Record System to Improve Tracking and Management of Patients Receiving Outpatient Parenteral Antibiotic Therapy.Open forum infectious diseases · 2024Article
- We Shape Our Tools and Then Our Tools Shape Us: OPAT and the EHR.Open forum infectious diseases · 2024Article
- Electronic health record-based readmission risk model performance for patients undergoing outpatient parenteral antibiotic therapy (OPAT).PLOS digital health · 2023Article
- Usefulness of Routine Laboratory Tests for Follow up of Patients Receiving Outpatient Parenteral Antimicrobial Therapy Run by Infectious Diseases Fellows.Antibiotics (Basel, Switzerland) · 2023Article
- Outcomes among patients withAntimicrobial stewardship & healthcare epidemiology : ASHE · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To characterize factors associated with increased risk of outpatient parenteral antimicrobial therapy (OPAT) complication. Design: Retrospective cohort study. Setting: Four hospitals within NYU Langone Health (NYULH). Patients: All patients aged ≥18 years with OPAT episodes who were admitted to an acute-care facility at NYULH between January 1, 2017, and December 31, 2020, who had an infectious diseases consultation during admission. Results: Overall, 8.45% of OPAT patients suffered a vascular complication and 6.04% suffered an antimicrobial complication. Among these patients, 19.95% had a 30-day readmission and 3.35% had OPAT-related readmission. Also, 1.58% of patients developed a catheter-related bloodstream infection (CRBSI). After adjusting for key confounders, we found that patients discharged to a subacute rehabilitation center (SARC) were more likely to develop a CRBSI (odds ratio [OR], 4.75; Conclusions: Discharge to an SARC is strongly associated with increased risks of readmission for OPAT-related complications and CRBSI. Loss to follow-up with the infectious diseases service is strongly associated with increased risk of readmission and CRBSI. CRBSI prevention during SARC admission is a critically needed public health intervention. Further work must be done for patients undergoing OPAT to improve their follow-up retention with the infectious diseases service.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.