Evidence map›Paper›PMID 36406102›Full record

ArticleMalawi medical journal : the journal of Medical Association of Malawi2022

Tracheostomy without mechanical ventilation in patients with traumatic brain injury at a tertiary referral hospital in Malawi: a cross sectional study.

Gift Mulima, Stein Atle Lie, Anthony Charles, Asma Bilal Hanif, Carlos G Varela, Leonard N Banza, Sven Young

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Malawi medical journal : the journal of Medical Association of Malawi, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06288724 (Potentially MOdifiable Factors To ImproVe Outcomes of Mechanically Ventilated Patients in ICUs in a Low-income Country), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06288724 unknown statusnot on this mapstarted 2024, after this paper: background citation

Potentially MOdifiable Factors To ImproVe Outcomes of Mechanically Ventilated Patients in ICUs in a Low-income Country: Rationale and Protocol for a Registry-embedded Prospective Observational Study

Typeobservational_patient_registrySponsorNat Intensive Care Surveillance - MORURan2024 to 2024Enrolled625ConditionsCritical Illness, Invasive Mechanical Ventilation, ICU Mortality, Developing Countries
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Gift MulimaDepartment of Surgery, Kamuzu Central Hospital, P.O. Box 149, Lilongwe, Malawi.
Stein Atle LieThe Norwegian Arthroplasty Registry, Haukeland University Hospital, Bergen, Norway.
Anthony CharlesDepartment of Surgery, University of North Carolina, 4008 Burnett Womack Bldg, CB 7050, Chapel Hill, NC, 27599 USA.
Asma Bilal HanifDepartment of Surgery, Kamuzu Central Hospital, P.O. Box 149, Lilongwe, Malawi.
Carlos G VarelaDepartment of Surgery, Kamuzu Central Hospital, P.O. Box 149, Lilongwe, Malawi.
Leonard N BanzaDepartment of Surgery, Kamuzu Central Hospital, P.O. Box 149, Lilongwe, Malawi.
Sven YoungDepartment of Surgery, Kamuzu Central Hospital, P.O. Box 149, Lilongwe, Malawi.
Kamuzu Central Hospital · MWHaukeland University Hospital · NOUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tracheostomy alone, without mechanical ventilation, has been advocated to maintain a free airway in patients with traumatic brain injury in low-income settings with minimal critical care capacity. However, no reports exist on the outcomes of this strategy. We examine the results of this practice at a central hospital in Malawi. Methods: This is a retrospective review of medical records and prospectively gathered trauma surveillance data of patients admitted to Kamuzu Central Hospital, with traumatic brain injury from January 2010 to December 2015. In-hospital mortality rates were examined according to registered traumatic brain injury severity and airway management. Results: In our analysis, 1875 of 2051 registered traumatic brain injury patients were included; 83.3% were male, mean age 32.6 (SD 12.9) years. 14.2% (n=267) of the patients had invasive airway management (endotracheal tube or tracheostomy) with or without mechanical ventilation. Mortality in severe traumatic brain injury treated with tracheostomy without mechanical ventilation was 42% (10/24) compared to 21% (14/68) in patients treated without intubation or tracheostomy (p= 0.043). Tracheostomies had an overall complication rate of 11%. Conclusion: Tracheostomy without mechanical ventilation in severe traumatic brain injury did not improve survival outcomes in our setting. Tracheostomy for severe traumatic brain injury cannot be recommended when mechanical ventilation is not available unless there are sufficient specialized human resources for follow up in the ward. Efforts to improve critical care facilities and human resource capacity to allow proper use of mechanical ventilation in severe traumatic brain injury should be a high priority in low-income countries where the burden of trauma is high.

Indexed as

Brain Injuries, TraumaticTracheostomyAdultCross-Sectional StudiesFemaleHumansMalawiMaleRespiration, ArtificialTertiary Care CentersTime Factorsairway managementcritical carein-hospital mortalitymechanical ventilationtracheostomytraumatic brain injury

Identifiers

PMID36406102
PMCPMC9641605
OpenAlexW4309659048

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.