Evidence map›Paper›PMID 36405746›Full record

ArticleFrontiers in immunology2022

Oocytes could rearrange immunoglobulin production to survive over adverse environmental stimuli.

Yang Wang, Fu-Qiang Luo, Yu-Hao He, Zhi-Xia Yang, Xin Wang, Cong-Rong Li, Bei-Qi Cai, Liang-Jian Chen, Zi-Bin Wang, Cui-Lian Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yang WangState Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
Fu-Qiang LuoState Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
Yu-Hao HeState Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
Zhi-Xia YangState Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
Xin WangState Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
Cong-Rong LiState Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
Bei-Qi CaiDepartment of Ultrasonography, SIR RUN RUN Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu, China.
Liang-Jian ChenState Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
Zi-Bin WangAnalysis and Test Center, Nanjing Medical University, Nanjing, Jiangsu, China.
Cui-Lian ZhangReproductive Medical Center, Henan Provincial People's Hospital and Reproductive Medical Center, People's Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yi-Chun GuanCenter for Reproductive Medicine, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Dong ZhangState Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
Nanjing Medical University · CNThird Affiliated Hospital of Zhengzhou University · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoglobulins are key humoral immune molecules produced and secreted by B lymphocytes at various stages of differentiation. No research has reported whether immunoglobulins are present in the non-proliferative female germ cells-oocytes-and whether they are functionally important for oocyte quality, self-protection, and survival. Herein, we found that IgG was present in the oocytes of immunodeficient mice; the

Indexed as

Germ CellsOocytesAnimalsCell DifferentiationFemaleImmunoglobulin GMiceRNA, MessengerImmunoglobulin GRNA, MessengerCsf1E. colienvironmental stimuliimmunoglobulinLPSoocytesssRNA

Identifiers

PMID36405746
PMCPMC9667025
OpenAlexW4308125158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.