Evidence map›Paper›PMID 36405713›Full record

ReviewFrontiers in immunology2022

Regulation of epigenetic modifications in the head and neck tumour microenvironment.

Huimin Liu, Dongxu Wang, Zhijing Yang, Shuangji Li, Han Wu, Jingcheng Xiang, Shaoning Kan, Ming Hao, Weiwei Liu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Huimin LiuDepartment of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Dongxu WangLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Zhijing YangDepartment of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Shuangji LiDepartment of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Han WuDepartment of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Jingcheng XiangDepartment of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Shaoning KanDepartment of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Ming HaoDepartment of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Weiwei LiuDepartment of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck tumours are common malignancies that are associated with high mortality. The low rate of early diagnosis and the high rates of local recurrence and distant metastasis are the main reasons for treatment failure. Recent studies have established that the tumour microenvironment (TME) can affect the proliferation and metastasis of head and neck tumours

Indexed as

Head and Neck NeoplasmsTumor MicroenvironmentDNA MethylationEpigenesis, GeneticHumansProtein Processing, Post-TranslationalDNA methylationhead and neck tumourshistone modificationncRNAsRNA modificationstumour microenvironment

Identifiers

PMID36405713
PMCPMC9667738
OpenAlexW4307452233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.