Evidence map›Paper›PMID 36405707›Full record

ReviewFrontiers in immunology2022

Systems biology approaches to investigate the role of granulomas in TB-HIV coinfection.

Alexis Hoerter, Eusondia Arnett, Larry S Schlesinger, Elsje Pienaar

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Molecular Epidemiology ofMicroorganisms · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alexis HoerterWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States.
Eusondia ArnettHost-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX, United States.
Larry S SchlesingerHost-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX, United States.
Elsje PienaarWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States.
Purdue University West Lafayette · USTexas Biomedical Research Institute · US

Funding

Effect of HIV infection on M.tuberculosis granuloma formation and evolutionR21AI145539 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI KULKARNI, SMITA, SCHLESINGER, LARRY S. · 2019 to 2020
$536k
NIAID NIH HHS R21 AI145539
6 · The paper itself

Abstract

The risk of active tuberculosis disease is 15-21 times higher in those coinfected with human immunodeficiency virus-1 (HIV) compared to tuberculosis alone, and tuberculosis is the leading cause of death in HIV+ individuals. Mechanisms driving synergy between

Indexed as

CoinfectionHIV-1HIV InfectionsTuberculosisGranulomaHumansSystems BiologygranulomaHIV - human immunodeficiency virussystems biologyTB-HIV coinfectiontuberculosis

Identifiers

PMID36405707
PMCPMC9670175
OpenAlexW4307871552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.