ArticleFrontiers in medicine2022
Salivary mental stress biomarkers in COVID-19 patients.
Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Salivary Stress Biomarkers (Chromogranin A and Secretory IgA): Associations with Anxiety and Depressive Symptoms in Healthcare Professionals.Nursing reports (Pavia, Italy) · 2025Article
- Immune Dysregulation in the Oral Cavity during Early SARS-CoV-2 Infection.Journal of dental research · 2024Article
- Salivary biomarkers as pioneering indicators for diagnosis and severity stratification of pediatric long COVID.Frontiers in cellular and infection microbiology · 2024Article
- High level of psychological stress in COVID-19 recovered individuals: role of copeptin as a potential biomarker.Frontiers in psychology · 2023Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: During the COVID-19 pandemic, mental health disorders and level of stress show a major increase compared to before the pandemic. Coronavirus-related stress is recently the leading cause of negative impacts on global mental health. Thus, maintaining positive mental health is as important as maintaining physical health during COVID-19. The aim of this study was to analyze salivary mental stress biomarkers as cortisol, alpha-amylase, and chromogranin A in hospitalized patients with COVID-19 to compare their potential relationship with stress symptoms. Material and methods: A total of 80 adult hospitalized patients with moderate COVID-19 disease and a control group ( Results: The patients group presented significantly higher levels of sCort, sAA, and sCgA compared with the control group. The correlation analysis showed a positive correlation with strong strength between sCort and sAA ( Conclusion: Data from our study demonstrated that salivary biomarkers are promising tools of exploring COVID-19 related stress.
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