Evidence map›Paper›PMID 36405542›Full record

ArticleEuropean heart journal. Case reports2022

The multidisciplinary management of a mechanical mitral valve thrombosis in pregnancy: a case report and review of the literature.

Jennifer M Wright, Natalie Bottega, Judith Therrien, Roupen Hatzakorzian, Jean Buithieu, Dominique Shum-Tim, Karen Wou, Amale Ghandour, Patricia Pelletier, William Li Pi Shan and 3 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jennifer M WrightDepartment of Medicine, McGill University, McGill University Health Centre, Montréal, Quebec, Canada.ORCID https://orcid.org/0000-0003-4518-4731
Natalie BottegaDepartment of Medicine, McGill University, McGill University Health Centre, Montréal, Quebec, Canada.
Judith TherrienDepartment of Medicine, Jewish General Hospital, Montréal, Quebec, Canada.
Roupen HatzakorzianDepartment of Anaesthesia, McGill University Health Centre, Montréal, Quebec, Canada.
Jean BuithieuDepartment of Medicine, McGill University, McGill University Health Centre, Montréal, Quebec, Canada.
Dominique Shum-TimDepartment of Surgery, McGill University Health Centre, Montréal, Quebec, Canada.
Karen WouDepartment of Obstetrics and Gynecology, McGill University Health Centre, Montréal, Quebec, Canada.
Amale GhandourDepartment of Surgery, McGill University Health Centre, Montréal, Quebec, Canada.
Patricia PelletierDepartment of Medicine, McGill University, McGill University Health Centre, Montréal, Quebec, Canada.
William Li Pi ShanDepartment of Anaesthesia, McGill University Health Centre, Montréal, Quebec, Canada.
Ian KaufmanDepartment of Anaesthesia, McGill University Health Centre, Montréal, Quebec, Canada.
Richard BrownDepartment of Obstetrics and Gynecology, McGill University Health Centre, Montréal, Quebec, Canada.
Isabelle MalhaméDepartment of Medicine, McGill University, McGill University Health Centre, Montréal, Quebec, Canada.ORCID https://orcid.org/0000-0002-9140-8735
McGill University Health Centre · CAJewish General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The management of anticoagulation for mechanical heart valves during pregnancy poses a unique challenge. Mechanical valve thrombosis is a devastating complication for which surgery is often the treatment of choice. However, cardiac surgery for prosthetic valve dysfunction in pregnant patients confers a high risk of maternofetal morbidity and mortality. Case summary: A 39-year-old woman in her first pregnancy at 30 weeks gestation presented to hospital with a mechanical mitral valve thrombosis despite therapeutic anticoagulation with low-molecular-weight heparin. She underwent an emergent caesarean section followed immediately by a bioprosthetic mitral valve replacement. This occurred after careful planning and organization on the part of a large multidisciplinary team. Discussion: A proactive, rather than reactive, approach to the surgical management of a mechanical valve thrombosis in pregnancy will maximize the chances of successful maternal and fetal outcomes.

Indexed as

Case reportLow-molecular-weight heparinMechanical heart valvePregnancySurgeryThrombosisWarfarin

Identifiers

PMID36405542
PMCPMC9668069
OpenAlexW4308023631

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.