Evidence map›Paper›PMID 36405500›Full record

ReviewNanophotonics (Berlin, Germany)2021

Plasmonic gold nanostars for synergistic photoimmunotherapy to treat cancer.

Yang Liu, Ericka Chorniak, Ren Odion, Wiguins Etienne, Smita K Nair, Paolo Maccarini, Gregory M Palmer, Brant A Inman, Tuan Vo-Dinh

Open access · goldAbstract readReview
In one paragraph

Review in Nanophotonics (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Growing Gold Nanostars on 3D Hydrogel Surfaces.Chemistry of materials : a publication of the American Chemical Society · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yang LiuDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Ericka ChorniakDepartment of Radiation Oncology, Duke University Medical Center, Durham, NC, 27710, USA.
Ren OdionDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Wiguins EtienneDivision of Urology, Duke University Medical Center, Durham, NC, 27710, USA.
Smita K NairDepartment of Surgery, Duke University Medical Center, Durham, NC, 27710, USA.
Paolo MaccariniFitzpatrick Institute of Photonics, Duke University, Durham, NC, 27708, USA.
Gregory M PalmerFitzpatrick Institute of Photonics, Duke University, Durham, NC, 27708, USA.
Brant A InmanFitzpatrick Institute of Photonics, Duke University, Durham, NC, 27708, USA.
Tuan Vo-DinhDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.ORCID https://orcid.org/0000-0003-3701-3326
Duke University · USDuke Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is the second leading cause of death and there is an urgent need to improve cancer management. We have developed an innovative cancer therapy named Synergistic Immuno Photothermal Nanotherapy (SYMPHONY) by combining gold nanostars (GNS)-mediated photothermal ablation with checkpoint inhibitor immunotherapy. Our previous studies have demonstrated that SYMPHONY photoimmunotherapy not only treats the primary tumor but also dramatically amplifies anticancer immune responses in synergy with checkpoint blockade immunotherapy to treat remote and unresectable cancer metastasis. The SYMPHONY treatment also induces a 'cancer vaccine' effect leading to immunologic memory and prevents cancer recurrence in murine animal models. This manuscript provides an overview of our research activities on the SYMPHONY therapy with plasmonic GNS for cancer treatment.

Indexed as

cancergold nanostarsphotoimmunotherapy

Identifiers

PMID36405500
PMCPMC9646244
OpenAlexW3197427340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.