Evidence map›Paper›PMID 36405106›Full record

ReviewWorld journal of gastroenterology2022

Epidemiology of liver cirrhosis and associated complications: Current knowledge and future directions.

Yuan-Bin Liu, Ming-Kai Chen

2 registry-linked trialsOpen access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 100 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 5 pooled it
23.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06062108 completednot on this mapstarted 2023, after this paper: background citation

Etude de la prévalence de la Douleur Chez le Patient Cirrhotique hospitalisé

TypeobservationalSponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur MerRan2023 to 2025Enrolled30ConditionsCirrhosis, Hepatic Fibrosis, Pain, Acute, Pain, ChronicArmsPain evaluation
NCT06121479 phase3enrolling by invitationnot on this mapstarted 2023, after this paper: background citation

Oral Branched-chain Amino Acid Supplementation for Decompensated Cirrhotic Patients: a Pilot Study

TypeinterventionalSponsorMahidol UniversityRan2023 to 2025Enrolled30ConditionsDecompensated Cirrhosis and AscitesArmsBranched-chain amino acid
3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 5 syntheses or guidelines pooled it, 164 citations in OpenAlex.

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  20. [Research advances on hepatic encephalopathy following transjugular intrahepatic portosystemic shunt].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Review

40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yuan-Bin LiuDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430000, Hubei Province, China.
Ming-Kai ChenDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430000, Hubei Province, China. kaimingchen@163.com.
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cirrhosis causes a heavy global burden. In this review, we summarized up-to-date epidemiological features of cirrhosis and its complications. Recent epidemiological studies reported an increase in the prevalence of cirrhosis in 2017 compared to in 1990 in both men and women, with 5.2 million cases of cirrhosis and chronic liver disease occurring in 2017. Cirrhosis caused 1.48 million deaths in 2019, an increase of 8.1% compared to 2017. Disability-adjusted life-years due to cirrhosis ranked 16th among all diseases and 7th in people aged 50-74 years in 2019. The global burden of hepatitis B virus and hepatitis C virus-associated cirrhosis is decreasing, while the burden of cirrhosis due to alcohol and nonalcoholic fatty liver disease (NAFLD) is increasing rapidly. We described the current epidemiology of the major complications of cirrhosis, including ascites, variceal bleeding, hepatic encephalopathy, renal disorders, and infections. We also summarized the epidemiology of hepatocellular carcinoma in patients with cirrhosis. In the future, NAFLD-related cirrhosis will likely become more common due to the prevalence of metabolic diseases such as obesity and diabetes, and the prevalence of alcohol-induced cirrhosis is increasing. This altered epidemiology should be clinically noted, and relevant interventions should be undertaken.

Indexed as

Esophageal and Gastric VaricesLiver NeoplasmsNon-alcoholic Fatty Liver DiseaseFemaleFibrosisGastrointestinal HemorrhageHumansLiver CirrhosisMaleBurdenCausesCirrhosisComplicationsCostEpidemiologyFeature

Identifiers

PMID36405106
PMCPMC9669831
OpenAlexW4307868840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.