Evidence map›Paper›PMID 36405064›Full record

ReviewChinese herbal medicines2022

Molecular mechanisms of anti-cancer bioactivities of seaweed polysaccharides.

Tingting Liu, Qing Li, Xu Xu, Guoxia Li, Chengwang Tian, Tiejun Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Chinese herbal medicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Polysaccharides fromMolecules (Basel, Switzerland) · 2024
    Pooled it
  2. Review
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  10. Recognition on pharmacodynamic ingredients of natural products.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tingting LiuSchool of Basic Medicine, Tianjin Medical University, Tianjin 300070, China.
Qing LiTianjin Pharmaceutical Research Institute, Tianjin 300462, China.
Xu XuTianjin Pharmaceutical Research Institute, Tianjin 300462, China.
Guoxia LiSchool of Basic Medicine, Tianjin Medical University, Tianjin 300070, China.
Chengwang TianTianjin Pharmaceutical Research Institute, Tianjin 300462, China.
Tiejun ZhangTianjin Pharmaceutical Research Institute, Tianjin 300462, China.
Tianjin Institute of Pharmaceutical Research (China) · CNTianjin Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seaweed is a traditional Chinese medicine homologous to food, in which polysaccharides are responsible for anti-cancer by enhancing immunity, inducing cancer cell apoptosis, inhibiting cancer cell invasion and metastasis or directly scavenging oxidative free radicals that induce cancer cell changes. Among them, regulating immunity and promoting cancer cell apoptosis are intensively studied due to the important role in preventing cancer. Here we reviewed seaweed in the apoptosis-inducing signaling pathways including PI3K/AKT, ROS and JNK and discussed challenges in studying seaweed.

Indexed as

anti-cancerapoptosisimmunomodulationseaweed polysaccharidessignal pathways

Identifiers

PMID36405064
PMCPMC9669349
OpenAlexW4280507291

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.