ArticleActa clinica Croatica2021
QUALITY OF LIFE IN PATIENTS WITH EPILEPSY - SINGLE CENTRE EXPERIENCE.
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Article in Acta clinica Croatica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
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4citing papers in PubMed, 2 pooled it
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review of the Anti-seizure and Antiepileptic Effects and Mechanisms of Piperine.Central nervous system agents in medicinal chemistry · 2025Pooled it
- A systematic review of non-invasive biomarkers for seizure forecasting in pediatric epilepsy patients.Frontiers in neurologyPooled it
- Health-related quality of life and associated factors among patients living with epilepsy of Mekelle City Hospitals, Northern Ethiopia: a multicenter observational study.Health and quality of life outcomes · 2026Observational
- Influence of Clinical Factors on the Quality of Life in Romanian People with Epilepsy-A Follow-Up Study in Real-Life Clinical Practice.Journal of personalized medicine · 2023Article
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Authors and funding
18 authors.
Andreja Bujan Kovač1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Željka Petelin Gadže1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Katarina Ivana Tudor1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Sibila Nanković1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Vlatko Šulentić1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Zdravka Poljaković1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Goran Mrak1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Monika Mudrovčić1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Ira Brezak1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Dragana Mijatović1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Filip Đerke1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Andrej Desnica1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Jakob Nemir1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Ivana Čajić1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Petra Nimac Kozina1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Biljana Đapić Ivančić1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Borislav Radić1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Sanja Hajnšek1Department of Neurology, Zagreb University Hospital Centre, School of Medicine, University of Zagreb,
Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy,
Affiliated Partner of the ERN EpiCARE, Zagreb, Croatia;
2Department of Neurosurgery, Zagreb University Hospital Centre, School of Medicine, University of Zagreb, Affiliated Partner of EUROCAN, Zagreb, Croatia;
3Dr. Fran Mihaljević University Hospital for Infectious Diseases, Zagreb, Croatia;
4Klinički studio, Private Psychology Practice, Zagreb, Croatia;
5Istrian Health Centre, Umag Section, Umag, Croatia;
6Department of Neurology, Dubrava University Hospital, School of Medicine, University of Zagreb,
Zagreb, Croatia;
7Sveti Ivan Psychiatric Hospital, Zagreb, Croatia.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A prospective study was carried out at the Zagreb University Hospital Centre to evaluate the relationship between epilepsy, antiepileptic drugs (AEDs) and quality of life (QoL) in patients with epilepsy (PE), and its association with depressive symptoms and sexual dysfunction (SD). QoL was assessed by use of the Quality of Life in Epilepsy-31 Inventory (QOLIE-31), SD by the Arizona Sexual Experiences Scale (ASEX), and depressive symptoms by the Hamilton Rating Scale for Depression (HAM-D17). The study included 108 PE (women 63% and men 37% men), mean age 39.54±15.91 years. Focal type epilepsy was diagnosed in 14.8%, generalized type in 35.2%, and both types were present in 40.7% of study patients. Drug-resistant epilepsy (DRE) was present in 44/108 and vagus nerve stimulation (VNS) was implanted in 27/44 patients. The mean response on QOLIE-31 was 62.88±17.21 with no significant differences according to gender, type of epilepsy, and age. A statistically significantly lower QoL was found in the 'Overall QoL' domain (35-55
Indexed as
EpilepsyVagus Nerve StimulationAdultAnticonvulsantsFemaleHumansMaleMiddle AgedProspective StudiesQuality of LifeYoung AdultAnticonvulsantsAntiepileptic drugsDrug-resistant epilepsyEpilepsyQOLIE-31Quality of lifeVagus nerve stimulation
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