Evidence map›Paper›PMID 36404982›Full record

ArticleInternational journal of ophthalmology2022

Association of

Rui-Juan Guan, Xin Yan, Ling Li, Ze-Feng Kang, Xiao-Ying Zhang, Huan-Juan Yang

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rui-Juan GuanSoochow University, Suzhou 215000, Jiangsu Province, China.
Xin YanEye Hospital, China Academy of Chinese Medical Sciences, Beijing 100043, China.
Ling LiDepartment of Ophthalmology, Qinghai Provincial People's Hospital, Xining 810007, Qinghai Province, China.
Ze-Feng KangEye Hospital, China Academy of Chinese Medical Sciences, Beijing 100043, China.
Xiao-Ying ZhangDepartment of Ophthalmology, Qinghai Provincial People's Hospital, Xining 810007, Qinghai Province, China.
Huan-Juan YangDepartment of Ophthalmology, Qinghai Provincial People's Hospital, Xining 810007, Qinghai Province, China.
Qinghai Provincial Peoples Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the association of complement factor H (

methodsThe study group consisted of 172 participants with symptoms of AMD who were examined and diagnosed between January 2019 and June 2020. The control group was composed of 120 healthy individuals. Each participant was required to provide two milliliters of peripheral blood for DNA extraction. Two single nucleotide polymorphisms (SNPs) of

resultsIn a high-altitude population, the nominally significant differences of rs800292 and rs9903's genotype AG frequencies were observed in the AMD group (

conclusionGenotype AG of rs800292 may be a protective factor for AMD. Conversely, rs9903 seems to be a risk factor for AMD. Therefore, allele G of rs800292 may be a protective factor, and allele A of rs9903, a risk factor for AMD in Qinghai high-altitude population.

Indexed as

age-related macular degenerationcomplement factor Hmicrotubule-associated protein 1 light chain 3 betapathogenesissingle nucleotide polymorphisms

Identifiers

PMID36404982
PMCPMC9631175
OpenAlexW4307247817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.