Evidence map›Paper›PMID 36404970›Full record

ArticleInternational journal of ophthalmology2022

Real-world outcomes of anti-vascular endothelial growth factor therapy for retinal vascular vein occlusion in Tibet, China.

Xue-Mei Zhu, Ying-Ying Yu, Sina Zhuoga, Xiao Dawa, Yong-Kang Zhou, Ouzhu Wangmu, Deji Yangzong, Fang An, Heng Miao, Ming-Wei Zhao

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xue-Mei ZhuDepartment of Ophthalmology & Clinical Centre of Optometry, Peking University People's Hospital, Eye Diseases and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Beijing 100044, China.
Ying-Ying YuDepartment of Ophthalmology & Clinical Centre of Optometry, Peking University People's Hospital, Eye Diseases and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Beijing 100044, China.
Sina ZhuogaDepartment of Ophthalmology, Tibet Autonomous Region People's Hospital, Lhasa 850010, Tibet Autonomous Region, China.
Xiao DawaDepartment of Ophthalmology, Tibet Autonomous Region People's Hospital, Lhasa 850010, Tibet Autonomous Region, China.
Yong-Kang ZhouDepartment of Ophthalmology, Tibet Autonomous Region People's Hospital, Lhasa 850010, Tibet Autonomous Region, China.
Ouzhu WangmuDepartment of Ophthalmology, Tibet Autonomous Region People's Hospital, Lhasa 850010, Tibet Autonomous Region, China.
Deji YangzongDepartment of Ophthalmology, Tibet Autonomous Region People's Hospital, Lhasa 850010, Tibet Autonomous Region, China.
Fang AnDepartment of Ophthalmology, Tibet Autonomous Region People's Hospital, Lhasa 850010, Tibet Autonomous Region, China.
Heng MiaoDepartment of Ophthalmology & Clinical Centre of Optometry, Peking University People's Hospital, Eye Diseases and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Beijing 100044, China.
Ming-Wei ZhaoDepartment of Ophthalmology & Clinical Centre of Optometry, Peking University People's Hospital, Eye Diseases and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Beijing 100044, China.
Tibet Autonomous Region People's Hospital · CNPeking University · CNPeking University People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the outcomes of intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents for patients with retinal vein occlusion (RVO) related-macular edema (ME) in Tibetan.

methodsA retrospective, observational, single-center study. The demographic and clinical data of 90 RVO Tibetan patients (93 eyes) treated with either ranibizumab or conbercept in Tibet Autonomous Region People's Hospital from Jan 2018 to December 2019 were collected.

resultsThe mean patient age was 56.8±10.6y, 45 (50%) of them were female. The mean living altitude was 3867.8±567.9 m. At the last visit, the best-corrected visual acuity (BCVA) significantly increased (52.2±21.8 letters) in comparison with the baseline (38.2±24.1 letters,

conclusionAnti-VEGF therapy is effective and safe in Tibetan patients for the treatment of RVO related ME.

Indexed as

anti-vascular endothelial growth factor therapyintravitrealmacular edemaretinal venous occlusive diseaseTibetvisual acuity

Identifiers

PMID36404970
PMCPMC9631184
OpenAlexW4307377973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.