ArticleiScience2022
Integration of Transcriptome and Metabolome Analyses Reveals the Mechanistic Basis for Cadmium Accumulation in Maize.
Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Genetic basis of cadmium accumulation and tolerance in maize seedlings uncovered through integrated linkage mapping and transcriptome analysis.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Effects of Cultivation Substrate Differences on Quality Formation and Polysaccharide Composition Characteristics ofJournal of fungi (Basel, Switzerland) · 2026Article
- The molecular mechanism of the α-linolenic acid metabolism pathway in rice in response to Cd stress.BMC plant biology · 2026Article
- Article
- Multiomics analysis reveals candidate genes and pathway involved in isoquinoline alkaloids in Zanthoxylum armatum DC. fruit.Plant molecular biology · 2025Article
- Effects of Biochar and Sepiolite on Pb and Cd Dynamics in Contaminated Soil with Different Corn Varieties.Toxics · 2025Article
- Nitrogen effects and genotypic variation in Cd absorption, translocation, and chemical forms in wheat.Frontiers in plant science · 2025Article
- Phosphorus-Solubilizing Bacteria Enhance Cadmium Immobilization and Gene Expression in Wheat Roots to Reduce Cadmium Uptake.Plants (Basel, Switzerland) · 2024Article
- Transcriptomic and physiological analyses of Trichoderma citrinoviride HT-1 assisted phytoremediation of Cd contaminated water by Phragmites australis.BMC microbiology · 2024Article
- The Influence of Cadmium on Fountain Grass Performance Correlates Closely with Metabolite Profiles.Plants (Basel, Switzerland) · 2023Article
- Effects of LPS fromMicroorganisms · 2023Article
- Mechanistic basis for mitigating drought tolerance by selenium application in tobacco (Frontiers in plant science · 2023Article
- Transcriptomics and metabolomics association analysis revealed the responses ofFrontiers in plant science · 2023Article
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7 authors.
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Abstract
Cadmium (Cd) pollution in soil has become a major environmental issue worldwide. However, the underlying molecular mechanism of low grain-Cd accumulation (GCA) in maize is still largely unknown. Herein, we report the mechanistic basis for low GCA in maize by a multiomics approach. The low GCA genotype L63 showed normal vacuolar formation and a lower capacity of xylem loading of Cd than the high-accumulator L42 under Cd stress. Transcriptomic sequencing identified 84 low-GCA-associated genes which are mainly involved in the S-adenosylmethionine (SAM) cycle, metal transport, and vacuolar sequestration. A metabolome analysis revealed that L63 plants had a more active SAM cycle and a greater capacity for terpenoid synthesis and phenylalanine metabolism than L42. Combining the analysis of transcriptome and metabolome characterized several genes as key genes involved in the determination of Cd accumulation. Our study identifies a mechanistic basis for low Cd accumulation in maize grains and provides candidate genes for genetic improvement of crops.
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