ArticleJournal of diabetes and metabolic disorders2022
Sensitivity and specificity of high frequency ultrasound score (DCEC) in diabetic peripheral neuropathy.
Article in Journal of diabetes and metabolic disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 8 citations in OpenAlex.
- Prediction of diabetic peripheral neuropathy in type 2 diabetes using high-frequency ultrasound and shear-wave elastography of the median and tibial nerves: a nomogram study.European journal of medical research · 2026Article
- Clinical value of high-frequency ultrasound and serum miR-92a-3p in diabetic peripheral neuropathy.Journal of diabetes investigation · 2025Article
- Association between intraneural blood flow of the sciatic nerve, peripheral neuropathies, and foot ulcers in patients with diabetes.Quantitative imaging in medicine and surgery · 2025Article
- Exploring the Diagnostic Value of High-Frequency Ultrasound Technology for Subcutaneous Lipohypertrophy in Diabetes Patients Receiving Insulin Injections.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
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Abstract
Objectives: To summarize the ultrasonic characteristics of peripheral nerve damage in type 2 diabetes and to verify the diagnostic value of DCEC score for DPN. Methods: A total of 289 patients with type 2 diabetes evaluated peripheral neuropathy with neuroultrasound and nerve conduction at the Affiliated Hospital of Guizhou Medical University from June 2016 to June 2020. According to the diagnostic criteria from 2017 guidelines of China, 289 patients with type 2 diabetes were divided into three groups: DPN group: 203 cases; subclinical group: 48 cases; and non-DPN group: 38 cases. Kruskal Wallis test was used to identify the differences and characteristics of ultrasound scores between the all groups. The best cut-off value, sensitivity and specificity of DCEC score were obtained by receiver operator characteristic curve. Taking the diagnostic standard of diabetes peripheral neuropathy as the "gold standard", the best diagnostic threshold, sensitivity and specificity were obtained by drawing the ROC curve of DCEC score, and then the diagnostic value of DCEC score for DPN was verified. Results: Compared with non-DPN group, DCEC score in DPN group was significantly higher (P < 0.05). Otherwise,according to the ROC curve, the best cut-off value of DCEC score for DPN diagnosis was 12.5 (sensitivity 69.7%, specificity 71.1%). Conclusions: The DCEC score system can effectively diagnose DPN with length-dependence,mainly including the increase of definition score.
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