Evidence map›Paper›PMID 36404794›Full record

ArticleInternational journal of bioprinting2022

In vitro Evaluation of a 20% Bioglass-Containing 3D printable PLA Composite for Bone Tissue Engineering.

Nicolas Söhling, Shahed Al Zoghool, Eva Schätzlein, Jonas Neijhoft, Karla Mychellyne Costa Oliveira, Liudmila Leppik, Ulrike Ritz, Edgar Dörsam, Johannes Frank, Ingo Marzi and 2 more

Open access · diamondAbstract read
In one paragraph

Article in International journal of bioprinting, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Nicolas SöhlingDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, Frankfurt am Main, Hessen, Germany.
Shahed Al ZoghoolDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, Frankfurt am Main, Hessen, Germany.
Eva SchätzleinInstitute of BioMedical Printing Technology, Darmstadt University of Technology, Darmstadt, Germany.
Jonas NeijhoftDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, Frankfurt am Main, Hessen, Germany.
Karla Mychellyne Costa OliveiraDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, Frankfurt am Main, Hessen, Germany.
Liudmila LeppikDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, Frankfurt am Main, Hessen, Germany.
Ulrike RitzDepartment of Orthopedics and Traumatology, Johannes Gutenberg-University Mainz, Mainz, Rheinland-Pfalz, Germany.
Edgar DörsamDepartment of Mechanical Engineering, Technical University of Darmstadt, Institute of Printing Science and Technology, Darmstadt, Hessen, Germany.
Johannes FrankDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, Frankfurt am Main, Hessen, Germany.
Ingo MarziDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, Frankfurt am Main, Hessen, Germany.
Andreas BlaeserInstitute of BioMedical Printing Technology, Darmstadt University of Technology, Darmstadt, Germany.
Dirk HenrichDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, Frankfurt am Main, Hessen, Germany.
Goethe University Frankfurt · DETechnical University of Darmstadt · DEJohannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D) printing is considered a key technology in the production of customized scaffolds for bone tissue engineering. In a previous work, we developed a 3D printable, osteoconductive, hierarchical organized scaffold system. The scaffold material should be osteoinductive. Polylactic acid (PLA) (polymer)/Bioglass (BG) (mineral/ion source) composite materials are promising. Previous studies of PLA/BG composites never exceed BG fractions of 10%, as increase of bioactive BG component negatively affects the printability of the composite material. Here, we test a novel, 3D printable PLA/BG composite with BG fractions up to 20% for its biological activity

Indexed as

BioglassBone tissue engineeringCompositeOsteoconductiveOsteoinductivePolylactic acid

Identifiers

PMID36404794
PMCPMC9668481
OpenAlexW4297834378

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.