Evidence map›Paper›PMID 36404792›Full record

ArticleInternational journal of bioprinting2022

Bioprinting-Associated Shear Stress and Hydrostatic Pressure Affect the Angiogenic Potential of Human Umbilical Vein Endothelial Cells.

Marius Köpf, Ramin Nasehi, Franziska Kreimendahl, Stefan Jockenhoevel, Horst Fischer

Abstract read
In one paragraph

Article in International journal of bioprinting, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Extrusion bioprinting: meeting the promise of human tissue biofabrication?Progress in biomedical engineering (Bristol, England) · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marius KöpfDepartment of Dental Materials and Biomaterials Research (ZWBF), RWTH Aachen University Hospital, Aachen, Germany.
Ramin NasehiDepartment of Dental Materials and Biomaterials Research (ZWBF), RWTH Aachen University Hospital, Aachen, Germany.
Franziska KreimendahlDepartment of Biohybrid and Medical Textiles (BioTex), Institute of Applied Medical Engineering, Helmholtz Institute Aachen, RWTH Aachen University, Aachen, Germany.
Stefan JockenhoevelDepartment of Biohybrid and Medical Textiles (BioTex), Institute of Applied Medical Engineering, Helmholtz Institute Aachen, RWTH Aachen University, Aachen, Germany.
Horst FischerDepartment of Dental Materials and Biomaterials Research (ZWBF), RWTH Aachen University Hospital, Aachen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioprinting-associated shear stress and hydrostatic pressure can negatively affect the functionality of dispensed cells. We hypothesized that these mechanical stimuli can potentially affect the angiogenic potential of human umbilical vein endothelial cells (HUVECs). A numerical simulation model was used to calculate the shear stress during microvalve-based droplet ejection. The impact of different levels of applied pressure and the resulting shear stress levels on the angiogenic potential of HUVECs was investigated after up to 14 days of cultivation.

Indexed as

AngiogenesisBioprintingFluid-dynamic finite element analysisHydrostatic pressureShear stress

Identifiers

PMID36404792
PMCPMC9668580

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.