Evidence map›Paper›PMID 36404728›Full record

ArticleThe Journal of school health2023

Test-to-Stay in Kindergarten Through 12th Grade Schools After Household Exposure to Severe Acute Respiratory Syndrome Coronavirus 2.

Zeni Scott, Diya M Uthappa, Tara K Mann, Hwasoon Kim, M A Brookhart, Laura Edwards, Zsolt Rak, Daniel K Benjamin, Kanecia O Zimmerman, ABC Science Collaborative

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of school health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zeni ScottDuke University Pediatric Pulmonary Division and Fellowship Program, Department of Pediatrics, Duke University School of Medicine, Box 104013 DUMC, Durham, NC, 27710.
Diya M UthappaDoctor of Medicine Program, Duke University School of Medicine, Durham, NC, 27701.
Tara K MannDuke Clinical Research Institute, Duke University, 300 W. Morgan Street, Durham, NC, 27522.
Hwasoon KimDuke Clinical Research Institute-Statistics, Duke University, 300 W. Morgan Street, Durham, NC, 27522.
M A BrookhartDepartment of Population Health Sciences, Duke University, Durham, NC, 27701.
Laura EdwardsDuke Clinical Research Institute - Statistics, Duke University, Durham, NC.
Zsolt RakDuke Clinical Research Institute-Statistics, Duke University, Durham, NC.
Daniel K BenjaminDepartment of Pediatrics, Division of Pediatric Infectious Diseases, Duke Clinical Research Institute, Duke University School of Medicine, Co-Chair, The ABC Science Collaborative, Durham Centre Suite 800, 300 W. Morgan St., Durham, NC, 27701-7044.
Kanecia O ZimmermanDepartment of Pediatrics, Division of Critical Care, Duke Clinical Research Institute, Duke University School of Medicine, Co-Chair, The ABC Science Collaborative, Durham Centre Suite 800, 300 W. Morgan St., Durham, NC, 27701-7044.ORCID 0000-0003-3748-6932
ABC Science CollaborativeDurham, NC, 27701.

Funding

COVID-19 Supplement - Center for Innovative TRIals in ChilDrEN and AdulTs (TRIDENT)U24TR001608 · NCATS · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K., BERNARD, GORDON RAPHAEL · 2016 to 2022
$177.0M
RADx-UP SAY YES COVID Test Study (S4)U24MD016258 · NIMHD · DUKE UNIVERSITY · PI COHEN-WOLKOWIEZ, MICHAEL, DAVE, GAURAV J · 2020 to 2023
$116.7M
SARS-CoV-2 Screening and Diagnostic testing for return to K-12 schoolsOT2HD107559 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K., ZIMMERMAN, KANECIA OBIE · 2021 to 2022
$5.0M
NCATS NIH HHS U24 TR001608NICHD NIH HHS HHSN275201000003CNICHD NIH HHS HHSN275201000003INICHD NIH HHS OT2 HD107559NIMHD NIH HHS U24 MD016258
6 · The paper itself

Abstract

backgroundTest-to-stay (TTS) is a strategy to limit school exclusion following an exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We evaluated the use of TTS within universally masked kindergarten through 12th grade (K-12) school settings following household SARS-CoV-2 exposure.

methodsThree hundred twenty-two participants were enrolled. Serial rapid antigen testing was performed up to 15 days post-exposure. Analysis-eligible participants completed the 15-day testing protocol, tested positive any time during the testing window, or received a negative test on or after day 9. Primary outcomes included within-school tertiary attack rate (TAR) (test positivity among close contacts of positive TTS participants), and school days saved among TTS participants.

resultsSeventy-three of 265 analysis-eligible participants tested positive for SARS-CoV-2 (secondary attack rate of 28% [95% CI: 16-63%]). Among 77 within-school close contacts, 2 were positive (TAR = 3% [95% CI: 1-5%]). Participant absences were limited to 338 days, resulting in 82% of 1849 school days saved. IMPLICATIONS FOR SCHOOL HEALTH POLICY, PRACTICE, AND EQUITY: TTS facilitates continued in-person learning and can greatly reduce the number of missed school days.

conclusionsWithin universally masked K-12 schools, TTS is a safe alternative to school exclusion following household SARS-CoV-2 exposure.

Indexed as

COVID-19SARS-CoV-2Educational StatusFamily CharacteristicsHumansSchoolsCOVID-19K-12 school communitiesrapid antigen testSARS-CoV-2test-to-stay

Identifiers

PMID36404728
PMCPMC10261908

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.