Evidence map›Paper›PMID 36404679›Full record

ReviewNucleus (Austin, Tex.)2022

Chromatin accessibility: methods, mechanisms, and biological insights.

Andrés R Mansisidor, Viviana I Risca

Open access · goldAbstract readReview
In one paragraph

Review in Nucleus (Austin, Tex.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 128 citations in OpenAlex.

  1. Review
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29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrés R MansisidorLaboratory of Genome Architecture and Dynamics, The Rockefeller University, New York, NY.ORCID 0000-0002-6607-4016
Viviana I RiscaLaboratory of Genome Architecture and Dynamics, The Rockefeller University, New York, NY.ORCID 0000-0003-2670-8704
Rockefeller University · US

Funding

Cross-regulation between loop extrusion, chromatin fiber structure and chromatin-associated RNAsDP2GM150021 · NIGMS · ROCKEFELLER UNIVERSITY · PI RISCA, VIVIANA I · 2022 to 2025
$2.5M
Mapping the short-range chromatin architecture of the repressive epigenomeF32GM140551 · NIGMS · ROCKEFELLER UNIVERSITY · PI MANSISIDOR, ANDRES · 2021 to 2023
$205k
NIGMS NIH HHS DP2 GM150021NIGMS NIH HHS F32 GM140551
6 · The paper itself

Abstract

Access to DNA is a prerequisite to the execution of essential cellular processes that include transcription, replication, chromosomal segregation, and DNA repair. How the proteins that regulate these processes function in the context of chromatin and its dynamic architectures is an intensive field of study. Over the past decade, genome-wide assays and new imaging approaches have enabled a greater understanding of how access to the genome is regulated by nucleosomes and associated proteins. Additional mechanisms that may control DNA accessibility

Indexed as

ChromatinNucleosomesChromatin Assembly and DisassemblyDNADNA ReplicationChromatinDNANucleosomesAccessibilityATAC-seqchromatincompactionheterochromatinHP1linker histonesMNase-seqphase separationtranscription

Identifiers

PMID36404679
PMCPMC9683059
OpenAlexW4309658698

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.