Evidence map›Paper›PMID 36404590›Full record

ArticleExperimental physiology2023

Changes in cerebral autoregulation and vasoreactivity after surgical aortic valve replacement: a prospective study.

Tiago Pedro, Andreia Costa, Juliana Ferreira, Ana Luísa Rocha, Elson Salgueiro, Gilberto Pereira, Elsa Azevedo, Pedro Castro

Open access · hybridAbstract read
In one paragraph

Article in Experimental physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tiago PedroDepartment of Neuroradiology, Centro Hospitalar Universitário de São João, E.P.E., Porto, Portugal.ORCID 0000-0003-3953-9049
Andreia CostaDepartment of Neurology, Centro Hospitalar Universitário de São João, E.P.E., Porto, Portugal.
Juliana FerreiraCardiovascular Research and Development Unit, Faculty of Medicine of University of Porto, Porto, Portugal.
Ana Luísa RochaDepartment of Neurology, Centro Hospitalar Universitário de São João, E.P.E., Porto, Portugal.
Elson SalgueiroDepartment of Cardiothoracic Surgery, Centro Hospitalar Universitário de São João, E.P.E, Porto, Portugal.
Gilberto PereiraDepartment of Neurology, Centro Hospitalar Universitário de São João, E.P.E., Porto, Portugal.
Elsa AzevedoDepartment of Neurology, Centro Hospitalar Universitário de São João, E.P.E., Porto, Portugal.
Pedro CastroDepartment of Neurology, Centro Hospitalar Universitário de São João, E.P.E., Porto, Portugal.
Universidade do Porto · PTHospital de São João · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NEW

findingsWhat is the central question of this study? How are dynamic cerebral autoregulation and brain vasoreactivity influenced by severe aortic stenosis and its surgical treatment? What are the main findings and their importance? Dynamic cerebral autoregulation is preserved in the long term in patients with severe aortic stenosis and does not change after surgical aortic valve replacement. However, carbon dioxide vasoreactivity is impaired in these patients. ABSTRACT: Surgical aortic valve replacement (SAVR) alters the natural course of severe aortic stenosis (AS). In this study, we aimed to determine the effects of the disease on dynamic cerebral autoregulation and vasoreactivity (VR) and to assess their changes after SAVR. We recruited 23 patients diagnosed with severe AS eligible for SAVR and 15 healthy matched controls. AS patients had lower mean VR to CO

Indexed as

Aortic Valve StenosisHeart Valve Prosthesis ImplantationAortic ValveCarbon DioxideHumansProspective StudiesRisk FactorsTreatment OutcomeCarbon Dioxideaortic valve stenosiscerebral autoregulationtranscranial Doppler ultrasound

Identifiers

PMID36404590
PMCPMC10103757
OpenAlexW4309514399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.