Evidence map›Paper›PMID 36404405›Full record

ArticleCancer biology & therapy2022

Challenges documenting racial disparities in Merkel cell carcinoma.

Mackenzie R Martin, Noreen Mohsin, Serena Vilasi, Danielle Reed, Isaac Brownell

Open access · goldAbstract read
In one paragraph

Article in Cancer biology & therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mackenzie R MartinDermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, USA.ORCID 0000-0002-9064-5587
Noreen MohsinDermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, USA.ORCID 0000-0002-5944-2271
Serena VilasiDermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, USA.ORCID 0000-0002-6887-3532
Danielle ReedDermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, USA.ORCID 0000-0002-4264-8935
Isaac BrownellDermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, USA.ORCID 0000-0002-0090-9914
National Institute of Arthritis and Musculoskeletal and Skin Diseases · US

Funding

Molecular pathogenesis and therapy innovation for Merkel cell carcinomaZIAAR041222 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI BROWNELL, ISAAC · 2022 to 2025
$4.0M
Intramural NIH HHS ZIA AR041222
6 · The paper itself

Abstract

Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin cancer that predominantly impacts White patients. Overall incidence and the proportion of minority patients with MCC are both rising. In the more common skin cancer, melanoma, racial disparities are well-documented in stage at presentation and patient survival. Whether racial and ethnic disparities exist in MCC remains unclear. The study of MCC disparities is hampered by limitations in data registries, including SEER and NCDB, and an evolving natural history due to the advent of immunotherapy. Published MCC immunotherapy clinical trials consistently reported the racial diversity among enrolled subjects but failed to include patients' ethnicities. Efforts to improve data capture in cancer registries and create multi-institutional clinical databases will allow for more effective study of racial and ethnic disparities in rare cancers like MCC. Such studies are needed to advance policies promoting equity in care.

Indexed as

Carcinoma, Merkel CellMelanomaSkin NeoplasmsHumansImmunologic FactorsImmunotherapyImmunologic Factorshealth disparitiesimmunotherapyMerkel cell carcinomaracial disparitiesrare diseasesskin cancersurvivaltumor registries

Identifiers

PMID36404405
PMCPMC9683062
OpenAlexW4309667750

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.