Evidence map›Paper›PMID 36404320›Full record

ArticleBMC endocrine disorders2022

Assessment of thyroid gland hormones and ultrasonographic abnormalities in medical staff occupationally exposed to ionizing radiation.

Sanaa A El-Benhawy, Enayat I Fahmy, Sherien M Mahdy, Galal H Khedr, Alyaa S Sarhan, Mohamed H Nafady, Yousef A Yousef Selim, Tarek M Salem, Nehal Abu-Samra, Hany A El Khadry

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC endocrine disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Article
  7. Effects of mobile phone electromagnetic radiation on thyroid glands and hormones inJournal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Sanaa A El-BenhawyRadiation Sciences Department, Medical Research Institute, Alexandria University, Alexandria, Egypt.ORCID https://orcid.org/0000-0002-4477-9808
Enayat I FahmyRadiation Sciences Department, Medical Research Institute, Alexandria University, Alexandria, Egypt.ORCID https://orcid.org/0000-0002-3493-371X
Sherien M MahdyNuclear Medicine and thyroid gland Department, Naser Institute for Research and Treatment, Nasr City, Egypt.ORCID https://orcid.org/0000-0002-6434-9661
Galal H KhedrRadiology and Medical Imaging, Faculty of Applied Medical Sciences, Misr University for Science & Technology, Giza, Egypt.ORCID https://orcid.org/0000-0002-3486-4646
Alyaa S SarhanRadiology and Medical Imaging, Faculty of Applied Medical Sciences, University of 6 October, Giza, Egypt.ORCID https://orcid.org/0000-0001-8160-3708
Mohamed H NafadyRadiology and Medical Imaging, Faculty of Applied Medical Sciences, Misr University for Science & Technology, Giza, Egypt.ORCID https://orcid.org/0000-0003-0068-5065
Yousef A Yousef SelimRadiology and Medical Imaging, Faculty of Applied Medical Sciences, Misr University for Science & Technology, Giza, Egypt.ORCID https://orcid.org/0000-0002-1107-9020
Tarek M SalemDepartment of Internal Medicine, (Endocrinology Unit), Faculty of Medicine, Alexandria University, Alexandria, Egypt.ORCID https://orcid.org/0000-0002-5731-9317
Nehal Abu-SamraDepartment of Basic Sciences, Faculty of Physical Therapy, Pharos University, Alexandria, Egypt. nehal_chemistry2005@yahoo.com.ORCID https://orcid.org/0000-0002-5952-7945
Hany A El KhadryApplied Medical Chemistry Department, Medical Research Institute, Alexandria University, Alexandria, Egypt.ORCID https://orcid.org/0000-0002-4621-4827
Alexandria University · EGMisr University for Science and Technology · EGNasser Institute hospital · EGOctober 6 University · EGPharos University in Alexandria · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIonizing radiation (IR) is high-energy radiation that has the potential to displace electrons from atoms and break chemical bonds. It has the ability to introduce mutations, DNA strand breakage, and cell death. Being a radiosensitive organ, exposure of the thyroid gland to IR can lead to significant changes in its function. AIM OF THE WORK: Was to measure the levels of thyroid hormones panel and ultrasonography abnormalities in medical staff occupationally exposed to IR. SUBJECTS AND

methodsA total of 120 subjects were divided into three main groups: Group I: radiation-exposed workers occupationally exposed to radioiodine (131I) (n = 40), Group II: radiation-exposed workers occupationally exposed to X-ray (n = 40), and Group III: non-exposed healthy professionals matched in age and sex with the previous groups (n = 40). Thyroid hormones panel including free triiodothyronine (fT3), free thyroxine (fT4), thyroid-stimulating hormone (TSH), anti-thyroperoxidase antibodies (anti-TPO), and thyroglobulin (Tg) were measured. Thyroid ultrasonography was performed. Oxidative stress markers such as malondialdehyde (MDA), hydrogen peroxide (H2O2), and total antioxidant capacity (TAC) were measured.

resultsGroup I had significantly higher fT3 levels than the control group. fT3 levels were considerably higher, while TSH was substantially lower in group II participants than in the control group. Tg was markedly lower in radiation-exposed workers. However, anti-TPO levels in radiation-exposed workers were significantly higher than in the control group. MDA and H

conclusionDespite low exposure doses, occupational exposure to IR affects the thyroid hormones and links with a higher likelihood of developing thyroid immune diseases.

Indexed as

Iodine RadioisotopesThyroid NoduleHumansHydrogen PeroxideMedical StaffRadiation, IonizingThyroid HormonesThyrotropinHydrogen PeroxideIodine-131Iodine RadioisotopesThyroid HormonesThyrotropinIonizing radiationRadioiodineThyroid glandUltrasoundX-ray

Identifiers

PMID36404320
PMCPMC9677629
OpenAlexW4309442764

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.