Evidence map›Paper›PMID 36404231›Full record

ReviewUrologic oncology2023

Implementation of a comprehensive prehabilitation program for patients undergoing radical cystectomy.

Woodson W Smelser, Jacob E Tallman, Veerain K Gupta, Bashir Al Hussein Al Awamlh, Niels V Johnsen, Daniel A Barocas, Cristina Kline-Quiroz, Carey A Tomlinson, Matthew D McEvoy, Jill Hamilton-Reeves and 1 more

Abstract readReview
In one paragraph

Review in Urologic oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Prehabilitation for patients undergoing neoadjuvant therapy prior to cancer resection: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Woodson W SmelserDivision of Urology, Washington University in St. Louis, MISSOURI, Saint Louis, MO. Electronic address: smelser@wustl.edu.
Jacob E TallmanDepartment of Urology, Vanderbilt University Medical Center.
Veerain K GuptaDepartment of Urology, Vanderbilt University Medical Center.
Bashir Al Hussein Al AwamlhDepartment of Urology, Vanderbilt University Medical Center.
Niels V JohnsenDepartment of Urology, Vanderbilt University Medical Center.
Daniel A BarocasDepartment of Urology, Vanderbilt University Medical Center.
Cristina Kline-QuirozDepartment of Physical Medicine and Rehabilitation, Vanderbilt University Medical Center.
Carey A TomlinsonDepartment of Physical Medicine and Rehabilitation, Vanderbilt University Medical Center.
Matthew D McEvoyDepartment of Anesthesiology, Vanderbilt University Medical Center.
Jill Hamilton-ReevesDepartment of Urology, The University of Kansas Health System.
Sam S ChangDepartment of Urology, Vanderbilt University Medical Center.
Vanderbilt University Medical Center · USUniversity Health System · USWashington University in St. Louis · US

Funding

Transgenic & Gene-Targeting Shared ResourceP30CA168524 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ROY A. JENSEN · 2012 to 2026
$40.1M
Effect of Immune-Enhancing Nutrition on Radical Cystectomy Outcomes- MERIT extensionR37CA218118 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI HAMILTON-REEVES, JILL REEVES · 2018 to 2024
$4.0M
NCI NIH HHS P30 CA168524NCI NIH HHS R37 CA218118
6 · The paper itself

Abstract

backgroundCoordinated preoperative optimization programs for radical cystectomy (RC) are limited and non-comprehensive. We evaluated the feasibility and acceptability of a coordinated, multi-faceted prehabilitation program for RC patients at a high-volume bladder cancer referral center.

methodsWe performed a narrative literature review for prehabilitation in bladder cancer management as of December 1, 2020, with specific emphasis on examining higher-level evidence sources. We selected domains with the highest level of evidence and recruited a multidisciplinary team of experts to design our program. We implemented a comprehensive prehabilitation program with a pre-defined order set as standard of care for all patients undergoing RC beginning February 1, 2021. Demographic and clinicopathologic data were collected prospectively. Rates of adherence to the prehabilitation program services were analyzed using Stata version 13.

resultsA total of 82 patients were enrolled between February - December 2021, of which 67 (81%) had undergone RC at data cutoff. Mean age was 68 years (SD 11) and 63 (76%) identified as male. Neoadjuvant chemotherapy (NAC) was utilized in 48 (59%) patients. The mean Charlson Comorbidity Index was 3.8 (SD 2.3). 100% of patients were screened for malnutrition, with 82% consuming nutritional supplements. Fifty-two percent of patients attended physical therapy pre-op. The 30-day and 30- to 90-day rates of complications were 56% and 40%, respectively. Resource length of stay (RLOS) declined after implementation of prehabilitation.

conclusionsImplementation of a comprehensive prehabilitation program at a high-volume bladder cancer referral center is feasible and has a modest effect on resource consumption and complications in our early experience.

Indexed as

CystectomyUrinary Bladder NeoplasmsAgedHumansMaleNeoadjuvant TherapyPostoperative ComplicationsPreoperative ExerciseComplicationsImplementation scienceOutcomesPrehabilitationQuality improvementRadical cystectomy

Identifiers

PMID36404231
PMCPMC13036760
OpenAlexW4309516959

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.