Observational studyBMC geriatrics2022
Carotid artery corrected flow time and respiratory variations of peak blood flow velocity for prediction of hypotension after induction of general anesthesia in elderly patients.
Observational study in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07777159 (Dynamic Changes in Carotid Artery Doppler Parameters Following Passive Leg Raising for Prediction of Post-Induction Hypotension in Patients Undergoing Elective Gastrointestinal Tumor Surgery), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dynamic Changes in Carotid Artery Doppler Parameters Following Passive Leg Raising for Prediction of Post-Induction Hypotension in Patients Undergoing Elective Gastrointestinal Tumor Surgery
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Preoperative patient risk factors for intraoperative hypotension: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- The Effect of Esketamine on Peripheral Vascular Resistance in Elderly Patients During Anesthesia Induction: A Single-Center, Double-Blind, Prospective, Randomized Controlled Study.Drug design, development and therapy · 2026Trial
- ED50 of ciprofol combined with sufentanil for fiberoptic bronchoscopy of different patient populations with pulmonary tuberculosis.BMC anesthesiology · 2024Trial
- Assessment of preload responsiveness by variation in peak aortic flow velocity in suprasternal window: A novel approach.Indian journal of anaesthesia · 2026Article
- Carotid corrected flow time as a sensitive indicator for early diagnosis and dynamic monitoring of hemorrhagic shock: A translational study from porcine model to clinical practice.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026Article
- The Impact of Passive Leg Raising on Corrected Carotid Flow Time and Inferior Vena Cava Diameter Before and After Fasting: An Ultrasound-Based Cross-Sectional Study.Health science reports · 2026Article
- Study on the correlation between changes in perfusion index under different body positions and the risk of hypotension after anesthetic induction.BMC anesthesiology · 2026Observational
- Position-Induced Change in Carotid Corrected Flow Time Predicts Spinal Hypotension in Cesarean Delivery.International journal of women's health · 2026Article
- Associations of accelerated biological aging with intraoperative hypotension in major surgery: a multicenter cohort study of 116,996 patients.Annals of medicine · 2025Article
- Article
- Observational
- Carotid corrected flow time and Doppler shock index for prediction of post-induction hypotension in patients undergoing elective abdominal surgery: a prospective observational study.Perioperative medicine (London, England) · 2025Article
- Exploring the predictive value of carotid Doppler ultrasound and clinical features for spinal anesthesia-induced hypotension: a prospective observational study.Perioperative medicine (London, England) · 2025Article
- Pericapsular Nerve Group Block in Combination with Lateral Femoral Cutaneous Nerve and Sacral Plexus Blocks for Hip Fracture: A Case Series.Journal of pain research · 2025Article
- The predictive role of carotid artery flow time for anesthesia-induced hypotension in high-risk elderly patients.Journal of clinical monitoring and computing · 2024Article
- Simultaneous Venous-Arterial Doppler Ultrasound During Early Fluid Resuscitation to Characterize a Novel Doppler Starling Curve: A Prospective Observational Pilot Study.Journal of intensive care medicine · 2024Observational
- Preoperative Ultrasound for the Prediction of Postinduction Hypotension: A Systematic Review and Meta-Analysis.Journal of personalized medicine · 2024Review
- The Reliability of Carotid Artery Doppler Ultrasonography Indices in Predicting Fluid Responsiveness during Surgery for Geriatric Patients: A Prospective, Observational Study.Healthcare (Basel, Switzerland) · 2024Article
- Carotid blood flow changes following a simulated end-inspiratory occlusion maneuver measured by ultrasound can predict hypotension after the induction of general anesthesia: an observational study.BMC anesthesiology · 2024Observational
- The impact of pre-rehydration guided by carotid corrected flow time on hypotension prevention following general anesthesia induction in patients undergoing gastrointestinal surgery: a prospective randomized controlled trial.Frontiers in medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostinduction hypotension is closely related to postoperative complications. Elderly patients with compromised cardiovascular compensatory reserve are more susceptible to hypotension after induction of general anesthesia. This study investigated whether the carotid artery corrected flow time (FTc) and respiratory variation of peak blood flow velocity in the common carotid artery (ΔVpeak) could predict postinduction hypotension in elderly patients.
methodsThis prospective observational study included elderly patients aged 65 to 75 who were scheduled for elective surgery under general anesthesia with ASA physical status class of I-II, without cardiovascular disease, hypertension, diabetes, or obesity. Anesthesia was induced by midazolam, sufentanil, and etomidate and was maintained by sevoflurane. The carotid artery FTc and ΔVpeak were measured by ultrasound before induction of anesthesia. Hemodynamic data were recorded before induction and then during the first 10 min after induction.
resultsNinety-nine patients were included in the final analysis, of whom 63 developed postinduction hypotension. The area under the receiver operating characteristic curves was 0.87 (0.78 to 0.93) for carotid artery FTc and 0.67 (0.56 to 0.76) for ΔVpeak, respectively. The optimal cutoff value for predicting postinduction hypotension was 379.1 ms for carotid artery FTc, with sensitivity and specificity of 72.2 and 93.7%, respectively. The best cutoff value was 7.5% for ΔVpeak, with sensitivity and specificity of 55.6 and 75.0%, respectively.
conclusionsThe carotid artery FTc is a reliable predictor of postinduction hypotension in elderly patients with ASA status of I or II, without cardiovascular disease, hypertension, diabetes, or obesity. Elderly patients with a carotid artery FTc less than 379.1 ms before anesthesia have a higher risk of postinduction hypotension.
trial registrationClinical Trial Registry on August 2nd, 2020 ( www.chictr.org.cn ; ChiCTR2000035190).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.