Observational studyBMC geriatrics2022
Incidence of falls and fall-related injuries and their predictive factors in frail older persons with cancer: a multicenter study.
Observational study in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025).Journal of evidence-based medicine · 2026Guideline
- Falls among geriatric cancer patients: a systematic review and meta-analysis of prevalence and risk across cancer types.BMC geriatrics · 2025Pooled it
- Characteristics of Inpatient Falls and Factors Associated with Fall-Related Fractures and Recurrent Falls in a Japanese University Hospital.Medical sciences (Basel, Switzerland) · 2026Article
- Burden and Determinants of Fall and its Related Injuries in the Elderly Population of Uttarakhand, India: A Community-based Cross-sectional Study.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2026Article
- Long-term frailty progression and mortality in hemodialysis: Impact of dialysis duration and baseline frailty in a nationwide Japanese cohort.Clinical and experimental nephrology · 2026Article
- Balance confidence predicts incident injurious falls in older adults: a longitudinal study.European geriatric medicine · 2026Article
- Incidence and associated factors of falls in patients with chemotherapy-induced peripheral neuropathy: a scoping review and evidence mapping.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Development and validation of a fall risk assessment scale for hospitalized cancer patients undergoing chemotherapy.BMC nursing · 2025Article
- Oncology nurses' knowledge, perceptions, and perceived barriers related to discussing physical activity with patients with cancer, including older adults.BMC nursing · 2025Article
- Fall injuries among patients in selected hospitals of nepal: A cross-sectional study.Scientific reports · 2025Article
- Factors associated with ADL-defined disability-free survival among patients with advanced cancer in a palliative care setting: a retrospective cohort study.BMC palliative care · 2025Article
- The relationship between frailty and depression in Chinese elderly prostate cancer patients following radical surgery: the mediating effect of sleep disturbances.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Falls, fear of falling, and lower body strength in a cohort of community-dwelling older adults with cancer.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2025Article
- The Impact of Demographics and Comorbidities on Fall Incidence and Prevalence in Older Adults.Research square · 2024Article
- Chemotherapy-Induced Peripheral Neuropathy and Falls in Cancer Survivors Relate to Digital Balance and Gait Impairments.JCO precision oncology · 2024Article
- Improved accuracy and efficiency of primary care fall risk screening of older adults using a machine learning approach.Journal of the American Geriatrics Society · 2024Article
- Falls and fall-related injuries: prevalence, characteristics, and treatment among participants of the Geelong Osteoporosis Study.Frontiers in public health · 2024Article
- Association between personality traits and concerns about falling among older patients: the mediating role of subjective age.Frontiers in public health · 2024Article
- Fall risk in older adults hospitalized with tumours: Contributing factors and prediction model.Nursing open · 2023Article
- Frequency, Characteristics, and Risk Factors for Falls at an Inpatient Cancer Rehabilitation Unit.JCO oncology practice · 2023Article
Corrections and comments
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Authors and funding
20 authors at 14 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFalls and fall-related injuries are a major public health problem. Data on falls in older persons with cancer is limited and robust data on falls within those with a frailty profile are missing. The aim of this study is to investigate the incidence and predictive factors for falls and fall-related injuries in frail older persons with cancer.
methodsThis study is a secondary data analysis from data previously collected in a large prospective multicenter observational cohort study in older persons with cancer in 22 Belgian hospitals (November 2012-February 2015). Patients ≥70 years with a malignant tumor and a frailty profile based on an abnormal G8 score were included upon treatment decision and evaluated with a Geriatric Assessment (GA). At follow-up, data on falls and fall-related injuries were documented.
resultsAt baseline 2141 (37.2%) of 5759 included patients reported at least one fall in the past 12 months, 1427 patients (66.7%) sustained an injury. Fall-related data of 3681 patients were available at follow-up and at least one fall was reported by 769 patients (20.9%) at follow-up, of whom 289 (37.6%) fell more than once and a fall-related injury was reported by 484 patients (62.9%). Fear of falling was reported in 47.4% of the patients at baseline and in 55.6% of the patients at follow-up. In multivariable analysis, sex and falls history in the past 12 months were predictive factors for both falls and fall-related injuries at follow-up. Other predictive factors for falls, were risk for depression, cognitive impairment, dependency in activities of daily living, fear of falling, and use of professional home care.
conclusionGiven the high number of falls and fall-related injuries and high prevalence of fear of falling, multifactorial falls risk assessment and management programs should be integrated in the care of frail older persons with cancer. Further studies with long-term follow-up, subsequent impact on cancer treatment and interventions for fall prevention, and integration of other important topics like medication and circumstances of a fall, are warranted.
trial registrationB322201215495.
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