Evidence map›Paper›PMID 36402952›Full record

Observational studyBMC emergency medicine2022

Role of CD8

Lei Yan, Yumei Chen, Yi Han, Chaoyang Tong

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Critical illness expands a transcriptionally distinct hypometabolic CD8bioRxiv : the preprint server for biology · 2026
    Article
  3. TIM-3, a potential target for sepsis therapy.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Predictive value of PD-1Scientific reports · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Viral reactivations and fungal infections in nonresolving acute respiratory distress syndrome.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  13. Article
  14. Article
  15. Heat shock protein 90α reduces CD8Cell death discovery · 2024
    Article
  16. Article
  17. Review
  18. Observational
  19. Article
  20. Cancer and sepsis.Clinical science (London, England : 1979) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lei Yan *Department of Emergency Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yumei Chen *Department of Emergency Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yi Han *Department of Emergency Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Chaoyang TongDepartment of Emergency Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. tong.chaoyang@zs-hospital.sh.cn.
Fudan University · CNThe First Affiliated Hospital, Sun Yat-sen University · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCD8

methodsA prospective observational study in an emergency department enrolled patients who were diagnosed with sepsis-associated ARDS according to the sepsis-3 criteria and Berlin definition. Peripheral blood samples were collected within 24 h post recruitment. CD8

resultsSixty-two patients with ARDS met the inclusion criteria. CD8

conclusionsCD8

Indexed as

Respiratory Distress SyndromeSepsisCD8-Positive T-LymphocytesHumansPrognosisProspective StudiesAcute respiratory distress syndromeCD8+ T cell exhaustionCoinhibitory receptorsPrognosisSepsis

Identifiers

PMID36402952
PMCPMC9675152
OpenAlexW4309417878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.