ArticleNature communications2022
How people wake up is associated with previous night's sleep together with physical activity and food intake.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Poor sleep is robustly correlated with accelerated aging but the evidence for causation is mixed.medRxiv : the preprint server for health sciences · 2026Article
- Thalamic dynamics orchestrate the recovery of tonic alertness during nocturnal sleep inertia.Communications biology · 2026Article
- Sleep disorders and sleep behaviors as predictors of neurodegenerative diseases.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Evaluation of in vitro and in vivo antidiabetic potential of hydromethanol extract and solvent fraction of the leaves ofMetabolism open · 2026Article
- Chronotype-specific associations of sleep-wake schedule with behavioral, physiological, and psychological parameters.Sleep advances : a journal of the Sleep Research Society · 2026Article
- The relationships between stress, physical activity, mood, cognitive-emotional abilities, personality traits, and sleep.BMC psychiatry · 2025Article
- Dose-dependent association between physical activity and mental health, and mitigation effects on risk behaviors.iScience · 2025Article
- The effects of total sleep deprivation on the circadian rhythms and psychophysiological factors in military cadets; a comparison between wakefulness in light and darkness.Frontiers in physiology · 2025Article
- Five million nights: temporal dynamics in human sleep phenotypes.NPJ digital medicine · 2024Article
- Individual sleep need is flexible and dynamically related to cognitive function.Nature human behaviour · 2024Review
- Shorter self-reported sleep duration is associated with worse virtual spatial navigation performance in men.Scientific reports · 2024Article
- Is Short Sleep Bad for the Brain? Brain Structure and Cognitive Function in Short Sleepers.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Sleep Apnea, Obesity, and Diabetes - an Intertwined Trio.Current diabetes reports · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
How people wake up and regain alertness in the hours after sleep is related to how they are sleeping, eating, and exercising. Here, in a prospective longitudinal study of 833 twins and genetically unrelated adults, we demonstrate that how effectively an individual awakens in the hours following sleep is not associated with their genetics, but instead, four independent factors: sleep quantity/quality the night before, physical activity the day prior, a breakfast rich in carbohydrate, and a lower blood glucose response following breakfast. Furthermore, an individual's set-point of daily alertness is related to the quality of their sleep, their positive emotional state, and their age. Together, these findings reveal a set of non-genetic (i.e., not fixed) factors associated with daily alertness that are modifiable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.