Evidence map›Paper›PMID 36402181›Full record

ArticleEnvironmental research2023

Non-essential and essential trace element mixtures and kidney function in early pregnancy - A cross-sectional analysis in project viva.

Pi-I D Lin, Andres Cardenas, Sheryl L Rifas-Shiman, Ami R Zota, Marie-France Hivert, Izzuddin M Aris, Alison P Sanders

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Prenatal metal exposures and kidney function in adolescence in Project Viva.Environmental health : a global access science source · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. A Review of in vivo Toxicity of Quantum Dots in Animal Models.International journal of nanomedicine · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Pi-I D LinDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA. Electronic address: p_lin@harvardpilgrim.org.
Andres CardenasDepartment of Epidemiology and Population Health, Stanford University, Stanford, CA, USA. Electronic address: andres.cardenas@stanford.edu.
Sheryl L Rifas-ShimanDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA. Electronic address: sheryl_rifas@harvardpilgrim.org.
Ami R ZotaDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USA. Electronic address: arz2124@cumc.columbia.edu.
Marie-France HivertDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA. Electronic address: MHIVERT@PARTNERS.ORG.
Izzuddin M ArisDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA. Electronic address: Izzuddin_Aris@harvardpilgrim.org.
Alison P SandersEnvironmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: APS109@pitt.edu.
Harvard University · USColumbia University Irving Medical Center · USStanford Health Care · USUniversity of Pittsburgh · US

Funding

Prenatal environmental determinants of health in young adulthood: a lifecourse approachR01HD034568 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI Marie-France Hivert, Emily Oken · 1998 to 2026
$20.6M
Common and distinct early environmental influences on cardiometabolic and respiratory health: Mechanisms and methodsUH3OD023286 · OD · HARVARD PILGRIM HEALTH CARE, INC. · PI OKEN, EMILY · 2018 to 2022
$11.7M
Common and distinct early environmental influences on cardiometabolic and respiratory health: Mechanisms and methodsUG3OD023286 · OD · HARVARD PILGRIM HEALTH CARE, INC. · PI KLEINMAN, KENNETH P., OKEN, EMILY · 2016 to 2017
$4.1M
Maintain and Enrich Resource Infrastructure for Project Viva: a pre-birth cohort with follow up into adolescenceR24ES030894 · NIEHS · HARVARD PILGRIM HEALTH CARE, INC. · PI OKEN, EMILY · 2020 to 2024
$2.0M
PRENATAL AND POSTNATAL EXPOSURE TO ENVIRONMENTAL MIXTURES: NEURODEVELOPMENT AND DNA METHYLATION BIOMARKERSR01ES031259 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI CARDENAS, ANDRES · 2020 to 2024
$1.9M
Children's Exposure to Metals, MicroRNAs and Biomarkers of Renal HealthR00ES027508 · NIEHS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SANDERS, ALISON P · 2018 to 2020
$738k
NICHD NIH HHS R01 HD034568NIEHS NIH HHS R00 ES027508NIEHS NIH HHS R01 ES031259NIEHS NIH HHS R24 ES030894NIH HHS UG3 OD023286NIH HHS UH3 OD023286
6 · The paper itself

Abstract

Some trace elements are established nephrotoxicants, yet their associations with kidney function remain understudied in the context of pregnancy, a time of substantial change in kidney physiology and function. We aimed to estimate the individual and joint associations of trace element mixtures with maternal kidney function during the 1st trimester of pregnancy (mean 9.7 gestational weeks). 1040 women from Project Viva contributed blood samples which were assessed for erythrocyte non-essential [arsenic (As), cadmium (Cd), cesium (Cs), mercury (Hg), lead (Pb)] and essential [barium (Ba), magnesium (Mg), manganese (Mn), selenium (Se), and Zinc (Zn)] trace elements, and plasma creatinine for kidney function. We estimated glomerular filtration rate using the Chronic Kidney Disease Epidemiology Collaboration (eGFR

Indexed as

MercuryRenal Insufficiency, ChronicSeleniumTrace ElementsCross-Sectional StudiesFemaleHumansKidneyLeadPregnancyLeadMercurySeleniumTrace ElementseGFRKidney functionPregnancyTrace elements

Identifiers

PMID36402181
PMCPMC9732973
OpenAlexW4309570828

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.