Evidence map›Paper›PMID 36402082›Full record

Trial reportThe International journal on drug policy2023

Incarceration history, antiretroviral therapy, and stigma: A cross-sectional study of people with HIV who inject drugs in St. Petersburg, Russia.

Benjamin J Bovell-Ammon, Simeon D Kimmel, Debbie M Cheng, Ve Truong, Amy Michals, Marina Vetrova, Kimberly Hook, Bulat Idrisov, Elena Blokhina, Evgeny Krupitsky and 2 more

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in The International journal on drug policy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03290391 (Linking Infectious and Narcology Care-Part II), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03290391 phase4completednot on this map

Linking Infectious and Narcology Care-Part II

TypeinterventionalSponsorBoston Medical CenterRan2018 to 2022Enrolled225ConditionsHIV Infection, Drug UseArmsRapid ART initiation, Pharmacotherapy for opioid use disorder, Strengths-based HIV case management
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Provider-patient experiences and HIV care utilization among people living with HIV who inject drugs in St. Petersburg, Russia.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Benjamin J Bovell-AmmonDepartment of Medicine, Boston Medical Center; and Boston University School of Medicine, 801 Massachusetts Avenue, Crosstown Center 2nd Floor, Boston, MA 02118, USA. Electronic address: benjamin.bovell-ammon@bmc.org.
Simeon D KimmelDepartment of Medicine, Boston Medical Center; and Boston University School of Medicine, 801 Massachusetts Avenue, Crosstown Center 2nd Floor, Boston, MA 02118, USA.
Debbie M ChengDepartment of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown Center 3rd Floor, Boston, MA 02118, USA.
Ve TruongDepartment of Medicine, Boston Medical Center; and Boston University School of Medicine, 801 Massachusetts Avenue, Crosstown Center 2nd Floor, Boston, MA 02118, USA.
Amy MichalsBiostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, 85 East Newton Street, M921, Boston, MA 02118, USA.
Marina VetrovaPavlov First St. Petersburg State Medical University, Lev Tolstoy Street, 6-8, St. Petersburg 197022, Russian Federation.
Kimberly HookDepartment of Psychiatry, Boston Medical Center and Boston University School of Medicine, 720 Harrison Avenue 9th Floor, Boston, MA 02118, USA.
Bulat IdrisovDepartment of Health Systems and Population Health, University of Washington, 3980 15th Ave NE, Seattle, WA 98195-1621, USA; Bashkir State Medical University, 3 Lenin Street, Ufa, Republic of Bashkortostan 450008, Russian Federation.
Elena BlokhinaPavlov First St. Petersburg State Medical University, Lev Tolstoy Street, 6-8, St. Petersburg 197022, Russian Federation.
Evgeny KrupitskyPavlov First St. Petersburg State Medical University, Lev Tolstoy Street, 6-8, St. Petersburg 197022, Russian Federation; V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology, Bekhtereva Street, 3, St. Petersburg 192019, Russian Federation.
Jeffrey H SametDepartment of Medicine, Boston Medical Center; and Boston University School of Medicine, 801 Massachusetts Avenue, Crosstown Center 2nd Floor, Boston, MA 02118, USA; Department of Community Health Sciences, Boston University School of Public Health, 801 Massachusetts Avenue, Crosstown Center 4th Floor, Boston, MA 02118, USA.
Karsten LunzeDepartment of Medicine, Boston Medical Center; and Boston University School of Medicine, 801 Massachusetts Avenue, Crosstown Center 2nd Floor, Boston, MA 02118, USA.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH, DEBBIE M. CHENG · 1998 to 2026
$51.7M
HIV and Other Infectious Consequences of Substance UseT32DA013911 · NIDA · MIRIAM HOSPITAL · PI TRACI C GREEN, JOSIAH D RICH · 2001 to 2026
$9.6M
BU Clinical HIV/AIDS Research Training Program (BU-CHART)T32AI052074 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Benjamin P. Linas · 2003 to 2026
$6.7M
Linking Russian Narcology and HIV Care to Enhance Treatment, Retention and Outcomes Part IIR01DA045547 · NIDA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2017 to 2021
$3.7M
The Lifespan/Brown Criminal Justice Research Program on Substance Use and HIVR25DA037190 · NIDA · MIRIAM HOSPITAL · PI CURT G BECKWITH · 2014 to 2026
$3.5M
Boston University Medical Campus-Massachusetts General Hospital Global Psychiatric Clinical Research Training ProgramT32MH116140 · NIMH · BOSTON MEDICAL CENTER · PI FRICCHIONE, GREGORY L, HENDERSON, DAVID C · 2018 to 2022
$1.6M
Retention and Re-Engagement in Treatment for Addiction following Serious Injection Related Infections (RETAIN)K23DA054363 · NIDA · BOSTON MEDICAL CENTER · PI KIMMEL, SIMEON · 2021 to 2025
$947k
NIAID NIH HHS P30 AI042853NIAID NIH HHS T32 AI052074NIDA NIH HHS K23 DA054363NIDA NIH HHS R01 DA045547NIDA NIH HHS R25 DA037190NIDA NIH HHS T32 DA013911NIMH NIH HHS T32 MH116140
6 · The paper itself

Abstract

backgroundThe HIV epidemic is intertwined with substance use and incarceration in Russia. The relationships between incarceration history, HIV treatment history, and stigma experiences among people with HIV (PWH) who inject drugs in Russia have not been well described.

methodsWe conducted a cross-sectional study of a cohort of PWH with opioid use disorder who inject drugs (n=201) recruited at a narcology (substance use treatment) hospital in St. Petersburg, Russia from September 2018 to December 2020. The primary analysis evaluated the association between self-reported prior incarceration and prior antiretroviral therapy (ART) initiation using multivariable logistic regression to adjust for demographic, social, and clinical covariates. We used multivariable linear regression models to analyze associations between prior incarceration and two secondary outcomes: HIV stigma score (11-item abbreviated Berger scale) and substance use stigma score (21-item combination of Substance Abuse Self-Stigma Scale and Stigma-related Rejection Scale).

resultsMean age was 37 (SD 5) years; 58.7% were male. Participants had been living with HIV for a mean of 13 (SD 6) years. Over two thirds (69.2%) of participants reported prior incarceration. One third (35.3%) of participants reported prior ART initiation. Prior incarceration was not significantly associated with prior ART initiation (AOR 1.76; 95% CI: 0.81, 3.83). Prior incarceration was associated with a lower HIV stigma score (adjusted mean difference in z-score: -0.50; 95%CI: -0.81, -0.19) but was not significantly associated with substance use stigma score (adjusted mean difference in z-score: -0.10; 95%CI: -0.42, 0.21).

conclusionPrior incarceration was common, and rates of prior ART initiation were low even though most participants had been living with HIV for at least a decade. We did not find an association between prior incarceration and prior ART initiation, which suggests a need to explore whether opportunities to initiate ART during or after incarceration are missed. CLINICAL TRIAL NUMBER: NCT03290391.

Indexed as

HIV InfectionsSubstance Abuse, IntravenousSubstance-Related DisordersAdultAnti-Retroviral AgentsCross-Sectional StudiesFemaleHumansMaleRussiaAnti-Retroviral AgentsCorrectional facilitiesDrug useEurope < RegionKey and vulnerable populationsOpioid use disorderPeople in prisons and closed settings

Identifiers

PMID36402082
PMCPMC9868071

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.