Evidence map›Paper›PMID 36401595›Full record

SynthesisInternational wound journal2023

A meta-analysis examined the effect of stoma on surgical site wound infection in colorectal cancer.

Zimeng Chang, Liang Liu, Canfang She, Wei Ren, Hua Chen, Caihong Zhou

Retracted Registry-linked trialOpen access · goldAbstract readReviewMeta-AnalysisRetracted Publication
In one paragraph

Synthesis in International wound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. It is linked to trial NCT06309368 (To Close or Not to Close), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06309368 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

To Close or Not to Close: Surgical Site Infection Rates in Ostomy Primary Closure With 0.1% Betaine/Polyhexanide Wound Irrigation Compared to Conventional Ostomy Closure by Secondary Intention

TypeinterventionalSponsorUniversity of Nevada, Las VegasRan2024 to 2029Enrolled84ConditionsSurgical Site Infection, Wound Surgical, Colorectal DisordersArmsPrimary Ostomy Closure with 0.1% Betaine/0.1% Polyhexanide Wound Irrigation, Pursestring Closure
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zimeng ChangDepartment of Hospital Infection Control, Affiliated Changsha Hospital, Hunan Normal University, Hunan, China.
Liang LiuSchool of Medicine, Hunan Normal University, Hunan, China.
Canfang SheSchool of Medicine, Hunan Normal University, Hunan, China.
Wei RenDepartment of Nursing, Xijing Hospital, Shaanxi, China.
Hua ChenSchool of Medicine, Hunan Normal University, Hunan, China.
Caihong ZhouDepartment of Hospital Infection Control, Affiliated Changsha Hospital, Hunan Normal University, Hunan, China.ORCID https://orcid.org/0000-0001-9429-3120
Hunan Normal University · CNXijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess the impact of a stoma on surgical site wound infection in colorectal cancer, we conducted a meta-analysis. A thorough review of the literature up to September 2022 revealed that 3223 participants had colorectal cancer at the start of the investigations; 258 of them had a stoma, while 2965 did not have a stoma. Using dichotomous or contentious methods and a random or fixed-effect model, odds ratios (OR) and mean difference (MD) with 95% confidence intervals (CIs) were estimated to evaluate the impact of a stoma on surgical site wound infection in colorectal cancer. The stoma present had significantly higher surgical site wound infections (OR, 4.37; 95% CI, 3.08-6.21; P < 0.001) with no heterogeneity (I2 = 12%) compared to stoma absent in colorectal cancer. The stoma present had significantly higher surgical site wound infections compared to the stoma absent in colorectal cancer. The low number of selected studies in the meta-analysis calls for care when analysing the results.

Indexed as

Colorectal NeoplasmsSurgical StomasColostomyHumansIleostomySurgical Wound Infectioncolorectal cancerstomasurgical site wound infections

Identifiers

PMID36401595
PMCPMC10088842
OpenAlexW4309392701

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.