Evidence map›Paper›PMID 36401586›Full record

ArticleESC heart failure2023

Fulminant myocarditis with COVID-19 infection having normal C-reactive protein and serial magnetic resonance follow-up.

Eisuke Usui, Eiki Nagaoka, Hiroshi Ikeda, Mari Ohmori, Susumu Tao, Taishi Yonetsu, Yasuhiro Maejima, Hirokuni Arai, Kisaki Amemiya, Yoshihiko Ikeda and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in ESC heart failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Fulminant Myocarditis with SARS-CoV-2 Infection: A Narrative Review from the Case Studies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Eisuke UsuiDepartment of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo, Tokyo, Japan.
Eiki NagaokaDepartment of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Hiroshi IkedaDepartment of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo, Tokyo, Japan.
Mari OhmoriDepartment of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo, Tokyo, Japan.
Susumu TaoDepartment of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo, Tokyo, Japan.
Taishi YonetsuDepartment of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo, Tokyo, Japan.
Yasuhiro MaejimaDepartment of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo, Tokyo, Japan.
Hirokuni AraiDepartment of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Kisaki AmemiyaDepartment of Pathology, National Cerebral and Cardiovascular Center, Osaka, Japan.
Yoshihiko IkedaDepartment of Pathology, National Cerebral and Cardiovascular Center, Osaka, Japan.
Tetsuo SasanoDepartment of Cardiovascular Medicine, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo, Tokyo, Japan.
Tokyo Medical and Dental University · JPNational Cerebral and Cardiovascular Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 44-year-old woman who was quarantined for 5 days after the diagnosis of coronavirus disease of 2019 (COVID-19) was transferred to our hospital with the complaint of chest pain. The patient was unvaccinated. Electrocardiography revealed ST elevation in the lateral leads. Echocardiographic biventricular dysfunction with oedematous wall thickening was identified. Cardiac enzyme levels were elevated; however, C-reactive protein (CRP) levels, and the coronary angiogram were normal. The patient required mechanical circulatory support to stabilize haemodynamics and was treated with remdesivir, baricitinib, and intravenous methylprednisolone. She recovered after 13 days of mechanical support. Serial cardiac magnetic resonance imaging revealed acute myocardial oedema and subsequent fibrosis. An endomyocardial biopsy on admission showed mild interstitial inflammatory infiltrates with endomyocardial fibrous thickening and mild interstitial fibrosis of the myocardium. Normal CRP levels suggested minor involvement of interleukin (IL)-6, supporting the efficacy of baricitinib.

Indexed as

COVID-19MyocarditisAdultAzetidinesC-Reactive ProteinFemaleFibrosisFollow-Up StudiesHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyPurinesPyrazolesSulfonamidesAzetidinesbaricitinibC-Reactive ProteinPurinesPyrazolesSulfonamidesCardiac magnetic resonanceCOVID-19C-reactive proteinFulminant myocarditis

Identifiers

PMID36401586
PMCPMC10053182
OpenAlexW4309411345

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.