Trial reportJournal of foot and ankle research2022
Health-related quality of life and associated factors in people with diabetes at high risk of foot ulceration.
Trial report in Journal of foot and ankle research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Beyond the wound: A scoping review of the psychosocial impact of diabetes-related foot ulcers.Diabetic medicine : a journal of the British Diabetic Association · 2026Article
- Health-Related Quality of Life and Psychological Impact on Patients Post-Amputation Due to Diabetic Foot Ulcer.Cureus · 2026Article
- Association between triglyceride-glucose (TyG) index and diabetic foot ulcers in adult inpatients with type 2 diabetes at hospital admission.Frontiers in clinical diabetes and healthcare · 2026Article
- Patient-Reported Experience (PREMs) and Outcome (PROMs) Measures in Diabetic Foot Disease Management-A Scoping Review.Journal of clinical medicine · 2025Review
- Correlation of anxiety and depression with pain in patients with diabetic foot ulcers and analysis of risk factors.World journal of psychiatry · 2025Article
- Cutaneous wound healing in type 2 diabetes db/db mice was impaired with specific changes in proinflammatory cytokine expression.Archives of dermatological research · 2025Article
- Determining confidence and anxiety of Australian community podiatrists in managing foot ulceration: A cross-sectional study.Journal of foot and ankle research · 2024Article
- How far has diabetes-related foot disease research progressed in Australia? A bibliometric review (1970-2023).Journal of foot and ankle research · 2024Review
- The Stress of Measuring Plantar Tissue Stress in People with Diabetes-Related Foot Ulcers: Biomechanical and Feasibility Findings from Two Prospective Cohort Studies.Sensors (Basel, Switzerland) · 2024Article
- Article
- Intersectionality, vulnerability and foot health inequity.Journal of foot and ankle research · 2023Article
- Habitual Physical Activity of People with or at Risk of Diabetes-Related Foot Complications.Sensors (Basel, Switzerland) · 2023Article
- The validity and reliability of the Diabetic Foot Scale-Short Form (DFS-SF) in the Turkish population: a methodological study.Turkish journal of medical sciences · 2023Article
- Current knowledge of morbidities and direct costs related to diabetic foot disorders: a literature review.Frontiers in endocrinology · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundThe health-related quality of life (HRQoL) of people with diabetes-related foot complications has been increasingly reported, mostly from studies of people with a foot ulcer. The aim of this study was to assess HRQoL and determine factors associated with HRQoL in people with diabetes at high risk of foot ulceration.
methodsIn all, 304 participants enrolled in the Diabetic Foot Temperature Trial (DIATEMP) were included in the cross-sectional analysis. HRQoL was measured by the RAND® 36-Item Short Form Health Survey (SF-36) at baseline. Potential factors associated with HRQoL were analysed using multiple linear regression analyses for the eight domains of the SF-36.
resultsParticipants were predominantly male (72%), mean age 64.6 (±10.5) years, 77% type 2 diabetes and mean duration of diabetes 20 (±14) years. Mean SF-36 domain scores for the General Health (49.2 ± 20.1), Role Physical (50.9 ± 44.7), Physical Function (58.5 ± 27.9) and Vitality domains (59.8 ± 21.6) were lower compared to the Mental Health (78.4 ± 18.0), Social Functioning (75.3 ± 24.2), Role Emotional (73.5 ± 38.9) and Bodily Pain (67.0 ± 27.0) domains. HRQoL was lower than Dutch population-based and general diabetes samples, but higher than in samples with an ulcer. Use of a walking aid was associated with lower HRQoL across all 8 SF-36 domains (β range - 0.20 to - 0.50), non-Caucasian descent was associated with lower HRQoL in 5 domains (β range - 0.13 to - 0.17). Not working, higher BMI and younger age were associated with lower HRQoL in 3 domains.
conclusionsPeople at high risk of diabetes-related foot ulceration have reduced HRQoL that varies across domains, with the physical domains most affected. Assessing mobility, ethnicity, BMI and job status may be useful in daily practice to screen for people who might benefit from interventions targeting HRQoL.
trial registrationNetherlands Trial Registration: NTR5403. Registered on 8 September 2015.
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