Evidence map›Paper›PMID 36401199›Full record

ArticleBMC psychiatry2022

Patient characteristics associated with retrospectively self-reported treatment outcomes following psychological therapy for anxiety or depressive disorders - a cohort of GLAD study participants.

Christopher Rayner, Jonathan R I Coleman, Megan Skelton, Cherie Armour, John Bradley, Joshua E J Buckman, Molly R Davies, Colette R Hirsch, Matthew Hotopf, Christopher Hübel and 19 more

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 9 institutions in 2 countries.

Christopher RaynerInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0003-2950-343X
Jonathan R I ColemanInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-6759-0944
Megan SkeltonInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-7619-349X
Cherie ArmourResearch Centre for Stress Trauma & Related Conditions (STARC), School of Psychology, Queen's University Belfast (QUB), Belfast, Northern Ireland, UK.ORCID 0000-0001-7649-3874
John BradleyNIHR BioResource, Cambridge University Hospitals NHS Foundation, Cambridge Biomedical Campus, Cambridge, UK.ORCID 0000-0002-7774-8805
Joshua E J BuckmanCentre for Outcomes Research and Effectiveness (CORE), Research Department of Clinical, Educational & Health Psychology, University College London, 1-19 Torrington Place, WC1E 7HB, London, UK.ORCID 0000-0002-2281-0907
Molly R DaviesInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0003-3483-9907
Colette R HirschInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0003-3579-2418
Matthew HotopfInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-3980-4466
Christopher HübelInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-1267-8287
Ian R JonesMRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.ORCID 0000-0001-5821-5889
Gursharan KalsiInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-5156-7176
Nathalie KingstonDepartment of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.ORCID 0000-0002-9190-2231
Georgina KrebsInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-5353-5645
Yuhao LinInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Dina MonssenInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0003-0080-0799
Andrew M McIntoshDivision of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-0198-4588
Jessica R MundyInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Alicia J PeelInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-6144-5412
Katharine A RimesInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0003-2634-455X
Henry C RogersInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0003-2531-7496
Daniel J SmithDivision of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-2267-1951
Abigail R Ter KuileInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-7869-3754
Katherine N ThompsonInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0003-1818-0428
David VealeInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-1717-4766
Janet WingroveSouth London and Maudsley NHS Foundation Trust, Denmark Hill, SE5 8AZ, London, UK.
James T R WaltersMRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.ORCID 0000-0002-6980-4053
Gerome BreenInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0003-2053-1792
Thalia C EleyInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. thalia.eley@kcl.ac.uk.ORCID 0000-0001-6458-0700
King's College London · GBCardiff University · GBCambridge University Hospitals NHS Foundation Trust · GBQueen's University Belfast · GBSouth London and Maudsley NHS Foundation Trust · GBUniversity College London · GBUniversity of Cambridge · GBUniversity of Edinburgh · GBUniversity of Glasgow · GB

Funding

Medical Research Council MR/L010305/1Medical Research Council MR/N001400/1Medical Research Council MR/V012878/1Wellcome Trust 201292/Z/16/Z
6 · The paper itself

Abstract

backgroundProgress towards stratified care for anxiety and depression will require the identification of new predictors. We collected data on retrospectively self-reported therapeutic outcomes in adults who received psychological therapy in the UK in the past ten years. We aimed to replicate factors associated with traditional treatment outcome measures from the literature.

methodsParticipants were from the Genetic Links to Anxiety and Depression (GLAD) Study, a UK-based volunteer cohort study. We investigated associations between retrospectively self-reported outcomes following therapy, on a five-point scale (global rating of change; GRC) and a range of sociodemographic, clinical and therapy-related factors, using ordinal logistic regression models (n = 2890).

resultsFour factors were associated with therapy outcomes (adjusted odds ratios, OR). One sociodemographic factor, having university-level education, was associated with favourable outcomes (OR = 1.37, 95%CI: 1.18, 1.59). Two clinical factors, greater number of reported episodes of illness (OR = 0.95, 95%CI: 0.92, 0.97) and higher levels of personality disorder symptoms (OR = 0.89, 95%CI: 0.87, 0.91), were associated with less favourable outcomes. Finally, reported regular use of additional therapeutic activities was associated with favourable outcomes (OR = 1.39, 95%CI: 1.19, 1.63). There were no statistically significant differences between fully adjusted multivariable and unadjusted univariable odds ratios.

conclusionTherapy outcome data can be collected quickly and inexpensively using retrospectively self-reported measures in large observational cohorts. Retrospectively self-reported therapy outcomes were associated with four factors previously reported in the literature. Similar data collected in larger observational cohorts may enable detection of novel associations with therapy outcomes, to generate new hypotheses, which can be followed up in prospective studies.

Indexed as

DepressionDepressive DisorderAdultAnxietyCohort StudiesHumansProspective StudiesRetrospective StudiesSelf ReportTreatment OutcomeCognitive behavioral therapyCounsellingMinimal phenotyping

Identifiers

PMID36401199
PMCPMC9675224
OpenAlexW4309466705

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.