Evidence map›Paper›PMID 36401092›Full record

ArticleCell and tissue research2023

A re-appraisal of mesenchymal-epithelial transition (MET) in endometrial epithelial remodeling.

Madelyn Spooner-Harris, Karl Kerns, Michal Zigo, Peter Sutovsky, Ahmed Balboula, Amanda L Patterson

Open access · hybridAbstract read
In one paragraph

Article in Cell and tissue research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Mechanisms of Regeneration and Fibrosis in the Endometrium.Annual review of cell and developmental biology · 2023
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Madelyn Spooner-HarrisDivision of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA.
Karl KernsDivision of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA.
Michal ZigoDivision of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA.
Peter SutovskyDivision of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA.
Ahmed BalboulaDivision of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA.
Amanda L PattersonDivision of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA. pattersonama@missouri.edu.ORCID http://orcid.org/0000-0001-8407-5437
University of Missouri · USUniversity of Missouri Health System · USIowa State University · US

Funding

Functional characterization of mesenchymal-epithelial transition (MET)-derived cells in normal endometrial regenerationR01HD102476 · NICHD · UNIVERSITY OF MISSOURI-COLUMBIA · PI PATTERSON, AMANDA · 2021 to 2025
$1.6M
National Institute of Child Health and Human Development R01HD102476NICHD NIH HHS R01 HD102476
6 · The paper itself

Abstract

Mesenchymal-epithelial transition (MET) is a mechanism of endometrial epithelial regeneration. It is also implicated in adenocarcinoma and endometriosis. Little is known about this process in normal uterine physiology. Previously, using pregnancy and menses-like mouse models, MET occurred only as an epithelial damage/repair mechanism. Here, we hypothesized that MET also occurs in other physiological endometrial remodeling events, outside of damage/repair, such as during the estrous cycle and adenogenesis (gland development). To investigate this, Amhr2-Cre-YFP/GFP mesenchyme-specific reporter mice were used to track the fate of mesenchymal-derived (MD) cells. Using EpCAM (epithelial marker), EpCAM

Indexed as

EndometriumUterusAnimalsCell DifferentiationEpithelial Cell Adhesion MoleculeEpithelial CellsEstrous CycleFemaleMicePregnancyEpithelial Cell Adhesion MoleculeEndometrial epithelial remodelingEndometrial regenerationEpithelial repairMesenchymal-epithelial transition (MET)Postnatal uterine maturation

Identifiers

PMID36401092
PMCPMC9889438
OpenAlexW4309666296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.