Evidence map›Paper›PMID 36401053›Full record

ArticleArchives of microbiology2022

The effects of different thermal and chemical stresses on release of outer membrane vesicles (OMVs) by ClearColi™.

Zohreh Sadat Hosseini Zadeh, Fahimeh Nemati, Elham Sharif, Elham Mohit

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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  3. E-cigarette liquids alter the biogenesis and properties ofFrontiers in cellular and infection microbiology · 2026
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  4. Antigen 43 associated withMicrobiology spectrum · 2025
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zohreh Sadat Hosseini ZadehDepartment of Biotechnology, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Fahimeh NematiDepartment of Biotechnology, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Elham SharifDepartment of Pharmaceutical Biotechnology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, No. 2660, Vali-E-Asr Ave, Tehran, 1991953381, Iran.
Elham MohitDepartment of Pharmaceutical Biotechnology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, No. 2660, Vali-E-Asr Ave, Tehran, 1991953381, Iran. e.mohit@sbmu.ac.ir.
Shahid Beheshti University of Medical Sciences · IRIslamic Azad University Medical Branch of Tehran · IR

Funding

Shahid Beheshti University of Medical Sciences 17235
6 · The paper itself

Abstract

The highly immunogenic properties of outer membrane vesicles (OMVs), small spherical nanoparticles commonly released by Gram-negative bacteria, led to their application as vaccine candidate. ClearColi™ is an engineered Escherichia coli strain, which does not produce endotoxic response in humans and is useful for production of OMV-based vaccines. Therefore, producing ClearColi™ OMVs with high yield attracts particular interest. As stresses can be removed by OMVs, they may affect OMVs release. We aimed to investigate the effects of culture temperature, chemical (NaCl, ethanol, EDTA, D-cycloserine, polymyxin B, 1-octanol, and H

Indexed as

Hydrogen PeroxideSodium ChlorideEdetic AcidEscherichia coliGram-Negative BacteriaHumansEdetic AcidHydrogen PeroxideSodium ChlorideClearColi™Escherichia coliOuter membrane vesicle (OMV)Stress

Identifiers

PMID36401053
OpenAlexW4309583153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.