Evidence map›Paper›PMID 36400974›Full record

ArticleArchives of microbiology2022

The small RNA STnc1480 contributes to the regulation of biofilm formation and pathogenicity in Salmonella typhimurium.

Jing Li, Chengcheng Ning, Na Li, Yun Guo, Chunhui Ji, Xiaozhen Zhu, Xingxing Zhang, Qingling Meng, Xianzhu Xia, Xuepeng Cai and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jing Li *College of Animal Science and Technology, Shihezi University, Shihezi, 832003, Xinjiang, China.ORCID http://orcid.org/0000-0002-4413-8197
Chengcheng Ning *College of Animal Science and Technology, Shihezi University, Shihezi, 832003, Xinjiang, China.ORCID http://orcid.org/0000-0002-7329-6661
Na Li *College of Animal Science and Technology, Shihezi University, Shihezi, 832003, Xinjiang, China.ORCID http://orcid.org/0000-0002-5762-3140
Yun GuoCollege of Animal Science and Technology, Shihezi University, Shihezi, 832003, Xinjiang, China.ORCID http://orcid.org/0000-0002-3261-0829
Chunhui JiCollege of Animal Science and Technology, Shihezi University, Shihezi, 832003, Xinjiang, China.ORCID http://orcid.org/0000-0002-2902-2188
Xiaozhen ZhuCollege of Animal Science and Technology, Shihezi University, Shihezi, 832003, Xinjiang, China.ORCID http://orcid.org/0000-0002-5873-3448
Xingxing ZhangInstitute of Animal Science and Veterinary Research, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, 832000, Xinjiang, China.ORCID http://orcid.org/0000-0002-9838-6962
Qingling MengCollege of Animal Science and Technology, Shihezi University, Shihezi, 832003, Xinjiang, China.ORCID http://orcid.org/0000-0002-1190-0114
Xianzhu XiaCollege of Animal Science and Technology, Shihezi University, Shihezi, 832003, Xinjiang, China.ORCID http://orcid.org/0000-0002-9357-2176
Xuepeng CaiState Key Lab of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, Gansu, China.ORCID http://orcid.org/0000-0001-5725-1968
Jun QiaoCollege of Animal Science and Technology, Shihezi University, Shihezi, 832003, Xinjiang, China. qj710625@shzu.edu.cn.ORCID http://orcid.org/0000-0001-5210-4379
Shihezi University · CNLanzhou Veterinary Research Institute · CNXinjiang Academy of Agricultural and Reclamation Science · CN

Funding

national key research and development program No. 2016YFD0500900the Key Scientific and Technological Project in Agriculture of Xinjiang Production and Construction Corps 2019GG026Youth Science and Technology Innovation Leader of Xinjiang Production and Construction Corps 2016BC001
6 · The paper itself

Abstract

Salmonella Typhimurium (STM) is one of the most important food-borne bacteria that seriously harms livestock and human beings, which is capable of regulating the expression of its own genes in a variety of ways to adapt to a wide variety of adverse environmental stresses. To understand the regulatory roles of sRNA STnc1480 on the capability of STM, the STnc1480 gene-deficient strain △STnc1480 and its complement strain △STnc1480/STnc1480 were generated, and the impacts of STnc1480 gene deficiency on the capability of responding to different environmental stresses, biofilm(BF)formation and pathogenicity were analyzed, respectively. Then the target genes that were regulated by STnc1480 were also analyzed and explored. Compared with parent and complement strains, the deficiency of the STnc1480 gene significantly reduced the BF formation. Moreover, the capacities of adhesion and invasiveness of the △STnc1480 strain to macrophages were also significantly reduced, while the LD

Indexed as

RNASalmonella typhimuriumAnimalsBacterial ProteinsBiofilmsGene Expression Regulation, BacterialHumansMiceRNA, MessengerVirulenceBacterial ProteinsRNARNA, MessengerBiofilmEnvironmental stresslpfA genePathogenicitySalmonella typhimuriumSTnc1480

Identifiers

PMID36400974
OpenAlexW4309582905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.