Evidence map›Paper›PMID 36400814›Full record

ArticleScientific data2022

SARS-CoV-2 RNA levels in Scotland's wastewater.

Livia C T Scorza, Graeme J Cameron, Roisin Murray-Williams, David Findlay, Julie Bolland, Brindusa Cerghizan, Kirsty Campbell, David Thomson, Alexander Corbishley, David Gally and 10 more

Open access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 1 country.

Livia C T Scorza *SynthSys and School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JD, UK.ORCID 0000-0002-0145-3592
Graeme J Cameron *Scottish Environment Protection Agency (SEPA), Strathallan House, Stirling, FK9 4TZ, UK.
Roisin Murray-WilliamsScottish Environment Protection Agency (SEPA), Strathallan House, Stirling, FK9 4TZ, UK.
David FindlayScottish Environment Protection Agency (SEPA), Strathallan House, Stirling, FK9 4TZ, UK.
Julie BollandScottish Environment Protection Agency (SEPA), Strathallan House, Stirling, FK9 4TZ, UK.
Brindusa CerghizanScottish Environment Protection Agency (SEPA), Strathallan House, Stirling, FK9 4TZ, UK.ORCID 0000-0002-7061-3182
Kirsty CampbellScottish Environment Protection Agency (SEPA), Strathallan House, Stirling, FK9 4TZ, UK.
David ThomsonScottish Environment Protection Agency (SEPA), Strathallan House, Stirling, FK9 4TZ, UK.ORCID 0000-0003-0075-9570
Alexander CorbishleyThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, UK.ORCID 0000-0002-7902-0914
David GallyThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, UK.ORCID 0000-0002-2566-0844
Stephen FitzgeraldThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, UK.
Alison LowThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, UK.
Sean McAteerThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, UK.
Adrian M I RobertsBiomathematics and Statistics Scotland, James Clerk Maxwell Building, The King's Buildings, Edinburgh, EH9 3FD, Scotland, UK.ORCID 0000-0003-3568-8741
Zhou FangBiomathematics and Statistics Scotland, James Clerk Maxwell Building, The King's Buildings, Edinburgh, EH9 3FD, Scotland, UK.
Claus-Dieter MayerBiomathematics and Statistics Scotland, James Clerk Maxwell Building, The King's Buildings, Edinburgh, EH9 3FD, Scotland, UK.
Anastasia FrantsuzovaBiomathematics and Statistics Scotland, James Clerk Maxwell Building, The King's Buildings, Edinburgh, EH9 3FD, Scotland, UK.ORCID 0000-0001-9489-5295
Sumy V BabySynthSys and School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JD, UK.
Tomasz ZielińskiSynthSys and School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JD, UK.ORCID 0000-0002-0194-5706
Andrew J MillarSynthSys and School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JD, UK. Andrew.Millar@ed.ac.uk.ORCID 0000-0003-1756-3654
Scottish Environment Protection Agency · GBRoslin Institute · GBBiomathematics and Statistics Scotland · GBUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nationwide, wastewater-based monitoring was newly established in Scotland to track the levels of SARS-CoV-2 viral RNA shed into the sewage network, during the COVID-19 pandemic. We present a curated, reference dataset produced by this national programme, from May 2020 to February 2022. Viral levels were analysed by RT-qPCR assays of the N1 gene, on RNA extracted from wastewater sampled at 162 locations. Locations were sampled up to four times per week, typically once or twice per week, and in response to local needs. We report sampling site locations with geographical coordinates, the total population in the catchment for each site, and the information necessary for data normalisation, such as the incoming wastewater flow values and ammonia concentration, when these were available. The methodology for viral quantification and data analysis is briefly described, with links to detailed protocols online. These wastewater data are contributing to estimates of disease prevalence and the viral reproduction number (R) in Scotland and in the UK.

Indexed as

COVID-19RNA, ViralHumansPandemicsSARS-CoV-2ScotlandWastewaterRNA, ViralWastewater

Identifiers

PMID36400814
PMCPMC9674653
OpenAlexW4309326517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.