Evidence map›Paper›PMID 36400287›Full record

ArticleExperimental eye research2023

Characterization of C-X-C chemokine receptor type 5 in the cornea and role in the inflammatory response after corneal injury.

Praveen K Balne, Suneel Gupta, Keele M Landon, Nishant R Sinha, Alexandria C Hofmann, Nicholas Hauser, Prashant R Sinha, Hu Huang, Duraisamy Kempuraj, Rajiv R Mohan

Open access · greenAbstract read
In one paragraph

Article in Experimental eye research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Praveen K BalneHarry S. Truman Memorial Veterans' Hospital, Columbia, MO, United States; One-Health Vision Research Program, Departments of Veterinary Medicine & Surgery and Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States.
Suneel GuptaHarry S. Truman Memorial Veterans' Hospital, Columbia, MO, United States; One-Health Vision Research Program, Departments of Veterinary Medicine & Surgery and Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States.
Keele M LandonHarry S. Truman Memorial Veterans' Hospital, Columbia, MO, United States; One-Health Vision Research Program, Departments of Veterinary Medicine & Surgery and Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States.
Nishant R SinhaHarry S. Truman Memorial Veterans' Hospital, Columbia, MO, United States; One-Health Vision Research Program, Departments of Veterinary Medicine & Surgery and Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States.
Alexandria C HofmannHarry S. Truman Memorial Veterans' Hospital, Columbia, MO, United States.
Nicholas HauserOne-Health Vision Research Program, Departments of Veterinary Medicine & Surgery and Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States.
Prashant R SinhaHarry S. Truman Memorial Veterans' Hospital, Columbia, MO, United States; One-Health Vision Research Program, Departments of Veterinary Medicine & Surgery and Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States.
Hu HuangMason Eye Institute, School of Medicine, University of Missouri, Columbia, MO, United States.
Duraisamy KempurajHarry S. Truman Memorial Veterans' Hospital, Columbia, MO, United States; One-Health Vision Research Program, Departments of Veterinary Medicine & Surgery and Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States.
Rajiv R MohanHarry S. Truman Memorial Veterans' Hospital, Columbia, MO, United States; One-Health Vision Research Program, Departments of Veterinary Medicine & Surgery and Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States; Mason Eye Institute, School of Medicine, University of Missouri, Columbia, MO, United States. Electronic address: mohanr@health.missouri.edu.
Missouri College · USHarry S. Truman Memorial Veterans' Hospital · USUniversity of Missouri · US

Funding

Regulation of blood-retinal barrier by placental growth factor.R01EY027824 · NEI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Hu Huang · 2017 to 2026
$4.2M
Turbo Eye Drops to Treat Ocular Toxicity and Blindness from Sulfur MustardU01EY031650 · NEI · UNIVERSITY OF MISSOURI-COLUMBIA · PI MOHAN, RAJIV RAVINDRA · 2020 to 2024
$3.7M
Novel approaches for corneal haze/fibrosis eliminationR01EY030774 · NEI · UNIVERSITY OF MISSOURI-COLUMBIA · PI MOHAN, RAJIV RAVINDRA · 2019 to 2022
$1.5M
Late/chronic corneal injury following threat chemical exposureR01EY034319 · NEI · UNIVERSITY OF MISSOURI-COLUMBIA · PI GUPTA, SUNEEL, MOHAN, RAJIV RAVINDRA · 2022 to 2024
$1.4M
BLRD VA I01 BX000357BLRD VA IK6 BX005646NEI NIH HHS R01 EY027824NEI NIH HHS R01 EY030774NEI NIH HHS R01 EY034319NEI NIH HHS U01 EY031650
6 · The paper itself

Abstract

C-X-C chemokine receptor type 5 (CXCR5) regulates inflammatory responses in ocular and non-ocular tissues. However, its expression and role in the cornea are still unknown. Here, we report the expression of CXCR5 in human cornea in vitro and mouse corneas in vivo, and its functional role in corneal inflammation using C57BL/6J wild-type (CXCR5

Indexed as

Burns, ChemicalCorneal InjuriesEye BurnsAlkaliesAnimalsCorneaEndothelial CellsHumansInflammationMiceMice, Inbred C57BLReceptors, ChemokineRNA, MessengerVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsAlkaliesReceptors, ChemokineRNA, MessengerVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsAlkali injuryCorneaCorneal fibrosisCorneal inflammationCXCR5CXCR5(−/−)

Identifiers

PMID36400287
PMCPMC11926993
OpenAlexW4309116591

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.