Evidence map›Paper›PMID 36400176›Full record

ArticleThe Journal of allergy and clinical immunology2023

Do upper respiratory viruses contribute to racial and ethnic disparities in emergency department visits for asthma?

Darlene Bhavnani, Matthew Wilkinson, Rebecca A Zárate, Susan Balcer-Whaley, Daniel S W Katz, Paul J Rathouz, Elizabeth C Matsui

Open access · greenAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Darlene BhavnaniDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex. Electronic address: Darlene.Bhavnani@Austin.utexas.edu.
Matthew WilkinsonDepartment of Pediatrics, Dell Medical School, University of Texas at Austin, Austin, Tex.
Rebecca A ZárateDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.
Susan Balcer-WhaleyDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.
Daniel S W KatzDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.
Paul J RathouzDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.
Elizabeth C MatsuiDepartment of Population Health, Dell Medical School, University of Texas at Austin, Austin, Tex.
The University of Texas at Austin · US

Funding

The effect of a housing mobility program on environmental exposures and asthma morbidity among low-income minority childrenR01ES026170 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI KEET, CORINNE, MATSUI, ELIZABETH C. · 2016 to 2025
$6.8M
CTSA K12 Program at The University of Texas Health Science Center at San AntonioK12TR004529 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ALISON G CAHILL, JOEL TSEVAT · 2023 to 2026
$4.1M
Institutional Career Development Core (KL2)KL2TR002646 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI TSEVAT, JOEL · 2018 to 2022
$3.4M
Environmental Control as Add-on Therapy in Urban Children with AsthmaR01ES023447 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2014 to 2018
$3.4M
Childhood Asthma: Disease Course and Lung Function Trajectories and Air Pollution ExposureR01ES035131 · NIEHS · UNIVERSITY OF TEXAS AT AUSTIN · PI Elizabeth C. Matsui, ROGER PENG · 2024 to 2026
$2.0M
Mentoring in Patient-Oriented Research on Asthma and the Indoor EnvironmentK24AI114769 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI MATSUI, ELIZABETH C. · 2015 to 2023
$1.6M
NCATS NIH HHS K12 TR004529NCATS NIH HHS KL2 TR002646NIAID NIH HHS K24 AI114769NIEHS NIH HHS R01 ES023447NIEHS NIH HHS R01 ES026170NIEHS NIH HHS R01 ES035131
6 · The paper itself

Abstract

backgroundThere are marked disparities in asthma-related emergency department (ED) visit rates among children by race and ethnicity. Following the implementation of coronavirus disease 2019 (COVID-19) prevention measures, asthma-related ED visits rates declined substantially. The decline has been attributed to the reduced circulation of upper respiratory viruses, a common trigger of asthma exacerbations in children.

objectivesTo better understand the contribution of respiratory viruses to racial and ethnic disparities in ED visit rates, we investigated whether the reduction in ED visit rates affected Black, Latinx, and White children with asthma equally.

methodsAsthma-related ED visits were extracted from electronic medical records at Dell Children's Medical Center in Travis County, Texas. ED visit rates among children with asthma were derived by race/ethnicity. Incidence rate ratios (IRRs) and 95% CIs were estimated by year (2019-2021) and season.

resultsIn spring 2019, the ED visit IRRs comparing Black children with White children and Latinx children with White children were 6.67 (95% CI = 4.92-9.05) and 2.10 (95% CI = 1.57-2.80), respectively. In spring 2020, when infection prevention measures were implemented, the corresponding IRRs decreased to 1.73 (95% CI = 0.90-3.32) and 0.68 (95% CI = 0.38-1.23), respectively.

conclusionsThe striking reduction of disparities in ED visits suggests that during nonpandemic periods, respiratory viruses contribute to the excess burden of asthma-related ED visits among Black and Latinx children with asthma. Although further investigation is needed to test this hypothesis, our findings raise the question of whether Black and Latinx children with asthma are more vulnerable to upper respiratory viral infections.

Indexed as

AsthmaCOVID-19ChildEmergency Service, HospitalEthnicityHumansTexasasthmachildrenCOVID-19disparityethnicityraceRespiratory virus

Identifiers

PMID36400176
PMCPMC9991974
OpenAlexW4309339018

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.