Evidence map›Paper›PMID 36399928›Full record

ArticleJournal of the neurological sciences2022

Secondhand smoke exposure is independently associated with stroke among non-smoking adults in West Africa.

Akinkunmi Paul Okekunle, Osahon Jeffery Asowata, Adekunle G Fakunle, Onoja Matthew Akpa, Fred S Sarfo, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Lukman Owolabi and 58 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the neurological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

68 authors at 18 institutions in 4 countries.

Akinkunmi Paul OkekunleDepartment of Medicine, University of Ibadan, Nigeria; Department of Food and Nutrition, Seoul National University, Republic of Korea. Electronic address: akinokekunle@gmail.com.
Osahon Jeffery AsowataDepartment of Epidemiology and Medical Statistics, University of Ibadan, Nigeria.
Adekunle G FakunleDepartment of Medicine, University of Ibadan, Nigeria; Department of Public Health, Osun State University, Osogbo, Nigeria.
Onoja Matthew AkpaDepartment of Epidemiology and Medical Statistics, University of Ibadan, Nigeria; Institute of Cardiovascular Diseases, University of Ibadan, Nigeria.
Fred S SarfoKwame Nkrumah University of Science and Technology, Ghana.
Albert AkpaluDepartment of Medicine, University of Ghana Medical School, Accra, Ghana.
Kolawole WahabDepartment of Medicine, University of Ilorin, Ilorin, Nigeria.
Reginald ObiakoDepartment of Medicine, Ahmadu Bello University, Zaria, Nigeria.
Morenikeji KomolafeObafemi Awolowo University, Ile-Ife, Nigeria.
Lukman OwolabiDepartment of Medicine, Aminu Kano Teaching Hospital, Kano, Nigeria.
Godwin O OsaigbovoJos University Teaching Hospital Jos, Nigeria.
Hemant K TiwariUniversity of Alabama at Birmingham, Birmingham, AL, USA.
Joshua AkinyemiDepartment of Epidemiology and Medical Statistics, University of Ibadan, Nigeria.
Carolyn JenkinsMedical University of South Carolina, SC, USA.
Oyedunni ArulogunDepartment of Health Promotion and Education, University of Ibadan, Nigeria.
Philip IbinaiyeDepartment of Medicine, Ahmadu Bello University, Zaria, Nigeria.
Lambert AppiahKwame Nkrumah University of Science and Technology, Ghana.
Atinuke M AgunloyeDepartment of Radiology, University of Ibadan, Nigeria.
Abiodun M AdeoyeDepartment of Medicine, University of Ibadan, Nigeria; Institute of Cardiovascular Diseases, University of Ibadan, Nigeria; Center for Genomic and Precision Medicine, University of Ibadan, Nigeria.
Joseph YariaDepartment of Medicine, University of Ibadan, Nigeria.
Benedict Calys-TagoeDepartment of Medicine, University of Ghana Medical School, Accra, Ghana.
Ezinne O UvereDepartment of Medicine, University of Ibadan, Nigeria.
Godwin OgboleDepartment of Radiology, University of Ibadan, Nigeria.
Francis AgyekumDepartment of Medicine, University of Ghana Medical School, Accra, Ghana.
Taofeek A SanniFederal Teaching Hospital, Ido-, Ekiti, Nigeria.
Ganiyu A AmusaJos University Teaching Hospital Jos, Nigeria.
Mayowa OgunronbiFederal Medical Centre, Abeokuta, Nigeria.
Samuel OlowookereFederal Medical Centre, Abeokuta, Nigeria.
Olayemi BalogunDepartment of Medicine, Ahmadu Bello University, Zaria, Nigeria.
James A OgunmodedeDepartment of Medicine, University of Ilorin, Ilorin, Nigeria.
Oladotun V OlalusiDepartment of Medicine, University of Ibadan, Nigeria.
Diala SamuelDepartment of Medicine, University of Ibadan, Nigeria.
Aliyu MandeDepartment of Medicine, Aminu Kano Teaching Hospital, Kano, Nigeria.
Musbahu RabiuDepartment of Medicine, Aminu Kano Teaching Hospital, Kano, Nigeria.
Philip AdebayoAga-Khan University Dar es Salaam, Tanzania.
Adeniyi SundayDepartment of Medicine, University of Ilorin, Ilorin, Nigeria.
Lucius Chidiebere ImohJos University Teaching Hospital Jos, Nigeria.
Ayodipupo S OguntadeDepartment of Medicine, University of Ibadan, Nigeria; Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Big Data Institute, Oxford Population Health, University of Oxford, UK.
Abiodun AjoseDepartment of Medicine, University of Ibadan, Nigeria.
Arti SinghKwame Nkrumah University of Science and Technology, Ghana.
Oluwayemisi T AdeegbeDepartment of Medicine, University of Ibadan, Nigeria.
Yaw MensahDepartment of Medicine, University of Ghana Medical School, Accra, Ghana.
Michael B FawaleObafemi Awolowo University, Ile-Ife, Nigeria.
Salaam AbdulJos University Teaching Hospital Jos, Nigeria.
Joyce IkuborDelta State University Teaching Hospital, Oghara, Delta State, Nigeria.
Afolaranmi TolulopeJos University Teaching Hospital Jos, Nigeria.
Isah S YahayaDepartment of Medicine, Aminu Kano Teaching Hospital, Kano, Nigeria.
Cynthia AkisanyaFederal Medical Centre, Abeokuta, Nigeria.
Chidi J OdoDepartment of Radiology, University of Ibadan, Nigeria.
Richard EfidiDepartment of Radiology, University College Hospital, Ibadan, Nigeria.
Innocent I ChukwuonyeFederal Medical Centre, Umuahia, Nigeria.
Vincent ShidaliFederal Medical Center, Keffi, Nigeria.
Akintunde AdebowaleObafemi Awolowo University, Ile-Ife, Nigeria.
Kenneth A OhagwuFederal Medical Centre, Umuahia, Nigeria.
Osimhiarherhuo O AdeleyeFederal Medical Centre, Abeokuta, Nigeria.
Henry IheonyeDepartment of Medicine, Federal Medical Centre, Lokoja, Nigeria.
Adeseye AkintundeLadoke Akintola University of Technology/Teaching Hospital, Ogbomosho, Nigeria.
Eunice OlabinriFederal Teaching Hospital, Ido-, Ekiti, Nigeria.
Josephine AkpaluDepartment of Medicine, University of Ghana Medical School, Accra, Ghana.
Julius AdesinaFederal Medical Centre, Abeokuta, Nigeria.
Ugochukwu OnyeonoroFederal Medical Centre, Umuahia, Nigeria.
Akinola OnasanyaSacred Heart Hospital Lantoro, Abeokuta, Ogun State, Nigeria.
Donna K ArnettUniversity of South Carolina, Columbia, SC, USA.
Daniel LacklandDepartment of Neurology, Medical University of South Carolina, USA.
Rufus AkinyemiFederal Medical Centre, Abeokuta, Nigeria; Center for Genomic and Precision Medicine, University of Ibadan, Nigeria; Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Bruce OvbiageleWeill Institute for Neurosciences, University of California San Francisco, USA.
Mayowa OwolabiDepartment of Medicine, University of Ibadan, Nigeria; Center for Genomic and Precision Medicine, University of Ibadan, Nigeria. Electronic address: mayowaowolabi@yahoo.com.
SIREN
University of Ibadan · NGFederal Medical Centre · NGJos University Teaching Hospital · NGUniversity of Ghana · GHAminu Kano Teaching Hospital · NGAhmadu Bello University · NGFederal Medical Centre · NGKwame Nkrumah University of Science and Technology · GHObafemi Awolowo University · NGUniversity of Ilorin · NGFederal Medical Centre · NGMedical University of South Carolina · USAga Khan University · TZDelta State University · NGUniversity College Hospital, Ibadan · NGUniversity of Alabama at Birmingham · USUniversity of California, San Francisco · USUniversity of South Carolina · US

Funding

H3Africa Administrative Coordinating Centre: Enabling and Supporting Genomics and Health Research Capacity Building in AfricaU24HG009780 · NHGRI · UNIVERSITY OF CAPE TOWN · PI SKELTON, MICHELLE · 2017 to 2022
$4.8M
Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
CNV And Stroke (CaNVAS)R01NS114045 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI COLE, JOHN W. · 2020 to 2024
$2.6M
African Rigorous Innovative Stroke Epidemiological Surveillance (ARISES)R01NS115944 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2020 to 2025
$2.2M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
Training Africans to Lead and Execute Neurological Trials & Studies (TALENTS)D43TW012030 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OVBIAGELE, BRUCE · 2021 to 2025
$1.2M
African Neurobiobank for Precision Stroke Medicine - (ELSI) ProjectU01HG010273 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI AKINYEMI, RUFUS OLUSOLA, ARULOGUN, OYEDUNNI SOLA · 2018 to 2022
$512k
Sub-Saharan Africa Conference on Stroke (SSACS) ConferenceR13NS115395 · NINDS · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI OVBIAGELE, BRUCE · 2020 to 2020
$50k
FIC NIH HHS D43 TW012030NHGRI NIH HHS U01 HG010273NHGRI NIH HHS U24 HG009780NHGRI NIH HHS U54 HG007479NINDS NIH HHS R01 NS107900NINDS NIH HHS R01 NS114045NINDS NIH HHS R01 NS115944NINDS NIH HHS R13 NS115395
6 · The paper itself

Abstract

backgroundStroke is a leading cause of disability and mortality worldwide, but little is known about the contribution of secondhand smoke exposure (SHSE) to stroke epidemiology among indigenous Africans.

objectiveTo evaluate the association of SHSE with stroke among indigenous Africans.

methodsWe analyzed the relationship of SHSE with stroke among 2990 case-control pairs of adults who had never smoked (identified in the SIREN study) using conditional logistic regression at a two-sided P < 0.05.

resultsMultivariable-adjusted odds ratio and 95% confidence interval; 1.25 (1.04, 1.50; P = 0.02) revealed SHSE was positively associated with stroke independent of stroke subtypes.

conclusionCulturally relevant primary prevention strategies targeted at SHSE might be promising in preventing stroke among Africans.

Indexed as

StrokeTobacco Smoke PollutionAdultAfrica, WesternBlack PeopleHumansOdds RatioTobacco Smoke PollutionHaemorrhagic strokeIschaemic strokeSecondhand smokingSIRENStroke

Identifiers

PMID36399928
PMCPMC9712270
OpenAlexW4308513693

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.