ReviewChemical reviews2023
Radiosynthesis, Preclinical, and Clinical Positron Emission Tomography Studies of Carbon-11 Labeled Endogenous and Natural Exogenous Compounds.
Review in Chemical reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Recent advances in [Nuclear medicine and biology · 2026Review
- Carbon-11 Production: Communication, Operations, Maintenance, Troubleshooting, and Analysis for Maintaining High-Grade Bombardment and Provisions of [Molecules (Basel, Switzerland) · 2026Article
- Reactive oxygen species (ROS)-responsive delivery of chlorantraniliprole by a nanoscale metal-phenolic network for systemic control of rice striped stem borer.Journal of nanobiotechnology · 2026Article
- Synthesis and Preclinical Evaluation of [ACS omega · 2026Article
- Synthesis, Radiochemistry, and Preclinical Assessment of the First GPR39 PET Imaging Agent.Journal of medicinal chemistry · 2026Article
- One-Pot Base-Free Suzuki-Miyaura [Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Synthetic Cadaver Odorants and the Sulfur Gap: Linking Chemistry and Canine Olfaction in Human Remains Detection.Molecules (Basel, Switzerland) · 2025Review
- Automated Manufacturing of Carbon-11 Radiopharmaceuticals Using Cassette-Based Radiosynthesizers.Journal of labelled compounds & radiopharmaceuticals · 2025Review
- Carbon isotopic labelling of carboxylic acids enabled by organic photoredox-catalysed cyanation.Nature synthesis · 2025Article
- Role of Radioiodine in Cancer Therapy: A Review of the Design and Challenges in Selecting Radioligands from Natural Sources.Drug design, development and therapy · 2025Review
- Radiotracers for Molecular Imaging of Angiotensin-Converting Enzyme 2.International journal of molecular sciences · 2024Review
- Reactive Palladium-Ligand Complexes forPharmaceuticals (Basel, Switzerland) · 2023Review
- Astrocyte Signature in Alzheimer's Disease Continuum through a Multi-PET Tracer Imaging Perspective.Cells · 2023Review
- Highlight selection of radiochemistry and radiopharmacy developments by editorial board.EJNMMI radiopharmacy and chemistry · 2023Review
- A Medicinal Chemistry Perspective on Excitatory Amino Acid Transporter 2 Dysfunction in Neurodegenerative Diseases.Journal of medicinal chemistry · 2023Review
- Recent Developments in Carbon-11 Chemistry and Applications for First-In-Human PET Studies.Molecules (Basel, Switzerland) · 2023Review
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
Abstract
The presence of positron emission tomography (PET) centers at most major hospitals worldwide, along with the improvement of PET scanner sensitivity and the introduction of total body PET systems, has increased the interest in the PET tracer development using the short-lived radionuclides carbon-11. In the last few decades, methodological improvements and fully automated modules have allowed the development of carbon-11 tracers for clinical use. Radiolabeling natural compounds with carbon-11 by substituting one of the backbone carbons with the radionuclide has provided important information on the biochemistry of the authentic compounds and increased the understanding of their
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.