Evidence map›Paper›PMID 36399692›Full record

ArticleJCO oncology practice2023

Shorter Radiation Regimens and Treatment Noncompletion Among Patients With Breast and Prostate Cancer in the United States: An Analysis of Racial Disparities in Access and Quality.

Edward Christopher Dee, Neil K Taunk, Fumiko L Chino, Curtiland Deville, Shearwood McClelland, Vinayak Muralidhar, Sean N McBride, Erin F Gillespie, Kosj Yamoah, Paul L Nguyen and 4 more

Open access · greenAbstract read
In one paragraph

Article in JCO oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
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  5. Dissemination and Implementation-A Primer for Accelerating "Time to Translation" in Radiation Oncology.International journal of radiation oncology, biology, physics · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 1 country.

Edward Christopher DeeDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0001-6119-0889
Neil K TaunkDepartment of Radiation Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Fumiko L ChinoDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0003-0498-488X
Curtiland DevilleDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0003-4846-6486
Shearwood McClellandDepartments of Radiation Oncology and Neurological Surgery, University Hospitals, Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH.ORCID 0000-0001-7951-9726
Vinayak MuralidharDepartment of Radiation Oncology, Dana Farber Cancer Institute/Brigham & Women's Hospital, Boston, MA.ORCID 0000-0003-1901-566X
Sean N McBrideDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-9676-1669
Erin F GillespieDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-1386-1542
Kosj YamoahCancer Epidemiology Program, Moffitt Cancer Center, Tampa, FL.ORCID 0000-0001-9055-3538
Paul L NguyenDepartment of Radiation Oncology, Dana Farber Cancer Institute/Brigham & Women's Hospital, Boston, MA.
Brandon A MahalDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL.
Karen M WinkfieldMeharry-Vanderbilt Alliance, Nashville, TN.ORCID 0000-0002-4996-8093
Neha VapiwalaDepartment of Radiation Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Patricia Mae G SantosDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.
Memorial Sloan Kettering Cancer Center · USBrigham and Women's Hospital · USUniversity of Pennsylvania · USJohns Hopkins University · USMeharry Medical College · USMoffitt Cancer Center · USUniversity Hospitals of Cleveland · USUniversity of Miami · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Leveraging implementation science to accelerate adoption of shorter-course radiation for breast and prostate cancerK08CA252640 · NCI · UNIVERSITY OF WASHINGTON · PI GILLESPIE, ERIN FAYE · 2020 to 2025
$1.3M
NCI NIH HHS K08 CA252640NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeCompared with conventional external-beam radiation therapy (cEBRT) for patients with breast cancer (BC) and prostate cancer (PC), shorter radiation regimens may be associated with lower treatment noncompletion rates. We assess disparities in receipt of shorter radiation regimens and treatment noncompletion for BC and PC. PATIENTS AND

methodsThe 2004-2017 National Cancer Database was queried for adjuvant cEBRT or hypofractionated EBRT (hEBRT) for nonmetastatic BC; and definitive cEBRT, moderate hypofractionation (mEBRT), or stereotactic body radiotherapy (SBRT) for localized PC. Multivariable logistic regression identified factors associated with treatment noncompletion and receipt of shorter regimens.

findingsWe identified 170,386 men with PC (median age [interquartile range], 70 [64-75] years; Black, 17.5%; White, 82.5%) and 306,846 women with BC (61 [52-69] years; Black, 12.3%; White, 87.7%). Among patients who received cEBRT for PC, Black men had higher treatment noncompletion rates compared with White (14.1%

interpretationBlack patients were consistently less likely to receive hypofractionated radiation for PC or BC, despite evidence suggesting that shorter regimens may lower rates of treatment noncompletion with similar oncologic outcomes.

Indexed as

Breast NeoplasmsProstatic NeoplasmsRadiosurgeryAgedHumansMaleRadiation Dose HypofractionationUnited States

Identifiers

PMID36399692
PMCPMC9970278
OpenAlexW4309410271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.