Evidence map›Paper›PMID 36399281›Full record

SynthesisJournal of occupational rehabilitation2023

Work Barriers and Job Adjustments of People with Multiple Sclerosis: A Systematic Review.

Bruno Kusznir Vitturi, Alborz Rahmani, Guglielmo Dini, Alfredo Montecucco, Nicoletta Debarbieri, Paolo Bandiera, Michela Ponzio, Mario Alberto Battaglia, Giampaolo Brichetto, Matilde Inglese and 2 more

Registry-linked trialAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of occupational rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06805318 (Development and Assessment of a Vocational Rehabilitation Intervention for Job Retention in Workers With Multiple Sclerosis), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06805318 narecruitingnot on this mapstarted 2025, after this paper: background citation

Development and Assessment of a Vocational Rehabilitation Intervention for Job Retention in Workers With Multiple Sclerosis (RiaLSM Intervention Project)

TypeinterventionalSponsorFondazione Italiana Sclerosi MultiplaRan2025 to 2025Enrolled30ConditionsMultiple Sclerosis, Vocational RehabilitationArmsVocational Rehabilitation intervention for pwMS
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  9. Identifying key determinants of work-related difficulties in multiple sclerosis: integrating clinical measures and socio-occupational factors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  10. Key Outcomes for a Vocational Rehabilitation Intervention for People With Multiple Sclerosis: A Nominal Group Technique Study.Health expectations : an international journal of public participation in health care and health policy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Bruno Kusznir VitturiDepartment of Health Sciences, University of Genoa, Building 3, L.Go R. Benzi, 10-16132, Genoa, Italy. bruno.kusznir.vitturi@edu.unige.it.ORCID http://orcid.org/0000-0002-2821-9042
Alborz RahmaniDepartment of Health Sciences, University of Genoa, Building 3, L.Go R. Benzi, 10-16132, Genoa, Italy.
Guglielmo DiniDepartment of Health Sciences, University of Genoa, Building 3, L.Go R. Benzi, 10-16132, Genoa, Italy.
Alfredo MontecuccoDepartment of Health Sciences, University of Genoa, Building 3, L.Go R. Benzi, 10-16132, Genoa, Italy.
Nicoletta DebarbieriIRCCS Ospedale Policlinico San Martino, Occupational Medicine Unit, Genoa, Italy.
Paolo BandieraItalian Multiple Sclerosis Association (AISM), Genoa, Italy.
Michela PonzioScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy.
Mario Alberto BattagliaScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy.
Giampaolo BrichettoItalian Multiple Sclerosis Association (AISM), Genoa, Italy.
Matilde IngleseDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI) and Center of Excellence for Biomedical Research (CEBR), University of Genoa, Genoa, Italy.
Benedetta PersechinoItalian Workers' Compensation Authority (INAIL), Rome, Italy.
Paolo DurandoDepartment of Health Sciences, University of Genoa, Building 3, L.Go R. Benzi, 10-16132, Genoa, Italy.
Ospedale Policlinico San Martino · ITAssociazione Italiana Sclerosi Multipla · ITUniversity of Genoa · ITIstituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose The aim was to carry out a systematic review dedicated to describing the work barriers and the job adjustments that are particularly sensitive to people with Multiple Sclerosis (PwMS). Methods Four electronic databases (PubMed/MEDLINE, Scopus, SciVerse ScienceDirect, and Web of Science) were searched for peer-reviewed original articles reporting the barriers at work and/or the job adjustments used by PwMS. MS must have been diagnosed according to accepted international criteria at the time of the study and/or confirmed by a doctor. No time limits were set for the search. Articles that were published in English, Italian, Spanish, French, and Portuguese were accepted. Each article was screened by three experienced and trained investigators. The protocol was registered in PROSPERO (CRD42022299994). Results The initial systematic search yielded 104,228 results, of which 49 articles provided sufficient information and were considered suitable for inclusion in the study. Overall, the studies included 30283 participants with MS. Thirteen (27.1%) studies reported on barriers to work, 14 (29.2%) addressed reasonable adjustments and 21 (43.7%) assessed both outcomes. Job characteristics are the most important barriers for PwMS. Other reported barriers concern the work environment, social relationships at work, negative work events and lack of information. PwMS are more vulnerable to the need for adjustments at the workplace, being the management of the workload the most commonly used one. Conclusions PwMS are exposed to a wide variety of work barriers and job adjustments. Future studies are still highly encouraged on the topic.

Indexed as

Multiple SclerosisHumansWorkplaceDemyelinating diseasesEmploymentMultiple sclerosisVocational rehabilitationWork

Identifiers

PMID36399281
OpenAlexW4309368742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.