Evidence map›Paper›PMID 36399227›Full record

ReviewAmerican journal of clinical dermatology2023

Real-Life Barriers to Diagnosis of Early Mycosis Fungoides: An International Expert Panel Discussion.

Emmilia Hodak, Larisa Geskin, Emmanuella Guenova, Pablo L Ortiz-Romero, Rein Willemze, Jie Zheng, Richard Cowan, Francine Foss, Cristina Mangas, Christiane Querfeld

Erratum issued Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in American journal of clinical dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07705386 (Development of an AI-Assisted Diagnostic Tool for Mycosis Fungoides and Other Cutaneous Lymphoproliferative Diseases Using Microscopic Image Analysis), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07705386 active not recruitingnot on this mapstarted 2026, after this paper: background citation

Development of an AI-Assisted Diagnostic Tool for Mycosis Fungoides and Other Cutaneous Lymphoproliferative Diseases Using Microscopic Image Analysis: A Training and Validation Study

TypeobservationalSponsorCairo UniversityRan2026 to 2026Enrolled463ConditionsCutaneous Lymphoproliferative Diseases, Mycosis Fungoides of Skin (Diagnosis), T Cell Dyscrasia, PLEVA-PLC SpectrumArmsAI-assisted histopathology image analysis
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Diagnostic delay in mycosis fungoides: Insights from China's first multicentre registry of 305 patients.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Defensive medicine in dermatological practice - Dermatopathology as a mirror of structural challenges.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Review
  9. Article
  10. The diagnosis of early-stage mycosis fungoides: Views held by experts and non-experts in cutaneous lymphoma.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
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  17. Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 10 institutions in 7 countries.

Emmilia HodakDivision of Dermatology, Rabin Medical Center, Beilinson Hospital, Tel Aviv University, 39 Jabotinsky Street, Petah Tiqva, 49100, Tel Aviv, Israel. hodakemmilia@gmail.com.ORCID http://orcid.org/0000-0002-1645-8038
Larisa GeskinColumbia University Medical Center, Columbia University, New York, NY, USA.
Emmanuella GuenovaUniversity Hospital Lausanne (CHUV) and Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Pablo L Ortiz-RomeroDepartment of Dermatology, Hospital 12 de Octubre, Institute i+12, CIBERONC, Medical School, University Complutense, Madrid, Spain.
Rein WillemzeLeiden University Medical Center, Leiden, The Netherlands.
Jie ZhengRuijin Hospital, Shanghai Jiaotong University, Shanghai, China.
Richard CowanChristie Hospital, The Christie School of Oncology, Manchester, UK.
Francine FossYale Cancer Center, Yale School of Medicine, New Haven, CT, USA.
Cristina MangasDermatology Department and Institute of Oncology of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Christiane QuerfeldDivision of Dermatology and Department of Pathology, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
City Of Hope National Medical Center · USColumbia University Irving Medical Center · USEnte Ospedaliero Cantonale · CHHospital Universitario 12 De Octubre · ESLeiden University Medical Center · NLRuijin Hospital · CNTel Aviv University · ILThe Christie Hospital · GBUniversity of Lausanne · CHYale Cancer Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Helsinn Helsinn Healthcare SANCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Mycosis fungoides (MF) is a rare, primary cutaneous T-cell lymphoma that is challenging to diagnose due to its heterogeneous clinical presentation and complex histology. The subtlety of the initial clinical appearance of MF can result in diagnostic delays and hesitancy to refer suspected cases to specialist clinics. An unmet need remains for greater awareness and education. Therefore, an international expert panel of dermatologists, oncologists, hematologists, and dermatopathologists convened to discuss and identify barriers to early and accurate MF diagnosis that could guide clinicians toward making a correct diagnosis. Confirmation of MF requires accurate assessment of symptoms and clinical signs, and subsequent correlation with dermatopathological findings. This review summarizes the expert panel's guidance, based on the literature and real-life experience, for dermatologists to help include MF in their list of differential diagnoses, along with simple clinical and histopathologic checklists that may help clinicians to suspect and identify potential MF lesions and reduce diagnostic delays.

Indexed as

Mycosis FungoidesSkin NeoplasmsDiagnosis, DifferentialHumans

Identifiers

PMID36399227
PMCPMC9673193
OpenAlexW4309287222

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.