Evidence map›Paper›PMID 36399188›Full record

ArticleVirchows Archiv : an international journal of pathology2023

Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci.

Anne Kristin Fischer, Birgid Schömig-Markiefka, Carina Heydt, Dominik Ratiu, Peter Mallmann, Jörn Meinel, Reinhard Büttner, Dietmar Schmidt, Alexander Quaas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anne Kristin FischerInstitute of Pathology, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany. Anne.Fischer1@uk-koeln.de.ORCID http://orcid.org/0000-0003-0665-9693
Birgid Schömig-MarkiefkaInstitute of Pathology, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Carina HeydtInstitute of Pathology, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Dominik RatiuDepartment Od Gynaecology, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Peter MallmannDepartment Od Gynaecology, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Jörn MeinelInstitute of Pathology, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Reinhard BüttnerInstitute of Pathology, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Dietmar SchmidtMedical Care Center for Histology, Cytology and Molecular Diagnostics Trier, Max-Planck-Straße 5, 54296, Trier, Germany.
Alexander QuaasInstitute of Pathology, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on the incidental finding of a FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci, a rare entity recently described by Jennifer N. Stall and Robert H. Young in a series of sixteen cases in 2019, displaying features differing from conventional adult granulosa cell tumour. Our aim is to specify the morphologic and molecular particularities of this presumably underrecognized finding, with a short presentation of the typical clinical context. Awareness of this rare and challenging neoplasm with indeterminate clinical course is crucial in routine diagnostics.

Indexed as

Granulosa Cell TumorOvarian NeoplasmsThecomaAdultFemaleForkhead Box Protein L2Forkhead Transcription FactorsHumansForkhead Box Protein L2Forkhead Transcription FactorsFOXL2 protein, humanAdult granulosa cell tumourFOXL2 mutationFunctioning ovarian neoplasmsReticulin stainingThecoma-like foci

Identifiers

PMID36399188
PMCPMC10326121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.