Evidence map›Paper›PMID 36399125›Full record

ArticleeLife2022

Mettl3-mediated m

Fu-Qing Jiang, Kun Liu, Jia-Xuan Chen, Yan Cao, Wu-Yun Chen, Wan-Ling Zhao, Guo-Hua Song, Chi-Qian Liang, Yi-Min Zhou, Huan-Lei Huang and 6 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 41 citations in OpenAlex.

  1. The Role of NMedComm · 2026
    Review
  2. Article
  3. Methyltransferase like 3 promotes thyroid folliculogenesisJournal of translational internal medicine · 2026
    Article
  4. Article
  5. NBiomolecules · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. mExperimental & molecular medicine · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. IncreasedInternational journal of molecular sciences · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 6 countries.

Fu-Qing Jiang *Key Laboratory of Regenerative Medicine of Ministry of Education, Department of Developmental & Regenerative Biology, Jinan University, Guangzhou, China.
Kun Liu *Key Laboratory of Regenerative Medicine of Ministry of Education, Department of Developmental & Regenerative Biology, Jinan University, Guangzhou, China.ORCID 0000-0003-3512-4516
Jia-Xuan Chen *Key Laboratory of Regenerative Medicine of Ministry of Education, Department of Developmental & Regenerative Biology, Jinan University, Guangzhou, China.
Yan CaoKey Laboratory of Regenerative Medicine of Ministry of Education, Department of Developmental & Regenerative Biology, Jinan University, Guangzhou, China.
Wu-Yun ChenKey Laboratory of Regenerative Medicine of Ministry of Education, Department of Developmental & Regenerative Biology, Jinan University, Guangzhou, China.
Wan-Ling ZhaoKey Laboratory of Regenerative Medicine of Ministry of Education, Department of Developmental & Regenerative Biology, Jinan University, Guangzhou, China.
Guo-Hua SongCollege of Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Science, Tai'an, China.
Chi-Qian LiangKey Laboratory of Regenerative Medicine of Ministry of Education, Department of Developmental & Regenerative Biology, Jinan University, Guangzhou, China.
Yi-Min ZhouKey Laboratory of Regenerative Medicine of Ministry of Education, Department of Developmental & Regenerative Biology, Jinan University, Guangzhou, China.
Huan-Lei HuangDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital & Guangdong Academy of Medical Sciences, Guangzhou, China.
Rui-Jin HuangDepartment of Neuroanatomy, Institute of Anatomy, University of Bonn, Bonn, Germany.
Hui ZhaoStem Cell and Regeneration TRP, School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, China.
Kyu-Sang ParkDepartment of Physiology, Wonju College of Medicine, Yonsei University, Wonju, Republic of Korea.
Zhenyu JuKey Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Guangzhou, China.
Dongqing CaiKey Laboratory of Regenerative Medicine of Ministry of Education, Department of Developmental & Regenerative Biology, Jinan University, Guangzhou, China.
Xu-Feng QiKey Laboratory of Regenerative Medicine of Ministry of Education, Department of Developmental & Regenerative Biology, Jinan University, Guangzhou, China.ORCID 0000-0002-5911-071X
Ministry of Education · NZChinese University of Hong Kong · HKGuangdong Academy of Medical Sciences · CNInstitute of Aging · CAShandong First Medical University · CNUniversity of Bonn · DEYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease is the leading cause of death worldwide due to the inability of adult heart to regenerate after injury.

Indexed as

MethyltransferasesMyocytes, CardiacAnimalsCell ProliferationMethylationMiceRNA, MessengerTranscription FactorsMethyltransferasesMettl3 protein, mouseRNA, MessengerTranscription Factorscell biologyheartm6AMettl3mouseregenerationregenerative medicinestem cells

Identifiers

PMID36399125
PMCPMC9674341
OpenAlexW4309297112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.